Interesting synergism in vitro between a recently introduced antibiotic, colistin methane sulphonate, and sulphonamide drugs is described. The observations were extended to polymyxin B sulphate and sulphonamides with essentially similar results. The combinations are bactericidal at therapeutic levels, the ratio of drugs to one another is not critical, and the effect is present over a fairly wid...

say 2 weeks later, the ulcer wouild inflame again, and we would be compelled to cover the cornea again, as has happened. Even 2-3 months later we have seen a weak relapse with a small hypopyon for a few days. As far as our observations go, the interval of at least 6 months has to be kept. It is surprising, how willingly our patients wait, till the set term is over. The re-opening is a simple pr...