نتایج جستجو برای: sustained virological response
تعداد نتایج: 1045619 فیلتر نتایج به سال:
patients and methods this cross - sectional study was conducted on 143 thalassemic patients with chronic hepatitis c, who were treated with a combination of peg-ifn and rbv regimen. the rs12979860 and rs8099917 polymorphisms were assessed as the most common polymorphisms near the il28b gene by the polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) method. objectives w...
A phase 2 study of an interferon-free combination daclatasvir (BMS-790052, Bristol-Meyers Squibb) plus GS-7977 (formerly PSI-7977, Pharmasset/Gilead), with or without ribavirin, showed that this regimen was well tolerated and that treatmentnaive patients with hepatitis C virus (HCV) genotype 1, 2, and 3 infection achieved high rates of early sustained virological responses (SVRs). Investigators...
One year of interferon therapy inhibits HBV replication in one third of the patients whereas long-term administration of oral nucleos(t)ide analogues is efficient in most of them, as long as early treatment adaptation in patients with partial virological response and resistance is provided. Following the demonstration of a more potent antiviral effect in terms of sustained virological response ...
BACKGROUND Because high serum low-density lipoprotein (LDL) and total cholesterol concentrations before treatment have been found to be significant positive prognostic factors for a sustained virological response to HCV therapy in monoinfected patients, the aim of this study was to assess this relationship in HIV-HCV-coinfected patients. METHODS Pretreatment fasting lipid parameters (in parti...
UNLABELLED GIFT-I is a phase 3 trial evaluating the efficacy and safety of a 12-week regimen of coformulated ombitasvir (OBV)/paritaprevir (PTV)/ritonavir (r) for treatment of Japanese hepatitis C virus genotype 1b-infected patients. It consists of a double-blind, placebo-controlled substudy of patients without cirrhosis and an open-label substudy of patients with compensated cirrhosis. Patient...
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