mahmoud a. khattab department of motmsoom,memk{oon oonoasu~owovw{}ogy and hepatology, minia university, p.o. box: 61111,, egypt +20-225197818;+20-862378181, [email protected]; department of motmsoom,memk{oon oonoasu~owovw{}ogy and hepatology, minia university, p.o. box: 61111,, egypt +20-225197818;+20-862378181, [email protected] mohammed eslam department of motmsoom,memk{oon oonoasu~owovw{}ogy and hepatology, minia university, p.o. box: 61111,, egypt +20-225197818;+20-862378181, [email protected] michele malaguarnera department of biochemistry, medical chemistry and molecular biology, university of catania, italy maria giordano department of biochemistry, medical chemistry and molecular biology, university of catania, italy cristina russo department of biochemistry, medical chemistry and molecular biology, university of catania, italy mariano malaguarnera department of internal medicine and systemic diseases, university of catania, italy +39-0957262008, [email protected]; department of internal medicine and systemic diseases, university of catania, italy +39-0957262008, [email protected]

ya wen viral hepatitis key laboratary, department of infectious disease, xiangya hospital, central south university; changsha, china yi xiang zheng viral hepatitis key laboratary, department of infectious disease, xiangya hospital, central south university; changsha, china de ming tan viral hepatitis key laboratary, department of infectious disease, xiangya hospital, central south university; changsha, china; viral hepatitis key laboratary, department of infectious disease, xiangya hospital, central south university, changsha, china. tel: +86-13958868582, fax: +86-073189753766

fateme zare department of immunology, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran hossein hadinedoushan department of immunology, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran; department of immunology, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran. tel: +98-3536285406, fax: +98-3536238561 mohsen akhondi meybodi depatment of gastrology, faculty of medicine, shahid sadoughi hospital, shahid sadoughi university of medical sciences, yazd, ir iran mahdi dehghanmanshadi department of immunology, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran seyyed ali mirghanizade bafghi department of immunology, reproductive immunology research center, shahid sadoughi university of medical sciences, yazd, ir iran mahmood vakili department of community, faculty of medicine, shahid sadoughi university of medical sciences, yazd, ir iran

h. forootan digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran. a. sharifi digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran. sh. mirmomen digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran. n. daryani digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran. h. ghofrani digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran. m. farahvash digestive research centel; tehran university of medical sciences, imam khomeini hospital, tehran.

A. SHARIFI, A. GHAVIDEL, F. MANSOURGHANAEI, H. FOROOTAN, H. MIRMOMEN, H. VOSOGHINIA, H. GHOFRANI, M. AMIRIAN, M. AZMI, M. FARAHVASH, M. NASIRI, M. TALEBI, M. ZAHEDI, N. DARYANI, SH. MIRMOMEN,

Bashir Hajibeigi, Bita Behnava, Hassan Abolghasemi, Kamran Bagheri Lankarani, Maryam Keshvari, Pegah Karimi Elizee, Seyed-Moayed Alavian, Seyed-Vahid Tabatabaei, Seyyed Mohammad Miri,

Marie-Louise C Vachon Stephanie H Factor Andrea D Branch Maria-Isabel Fiel Maribel Rodriguez-Torres Norbert Bräu Richard K Sterling Jihad Slim Andrew H Talal Douglas T Dieterich Mark S Sulkowski

Beti Todorovska Nenad Joksimovic Viktorija Caloska-Ivanova Magdalena Dimitrova-Genadieva Meri Trajkovska Elena Curakova Sanja Kiprijanovska Beti Zafirova-Ivanovska Vladimir Serafimoski

mahtab daneshvar department of hepatitis and aids, pasteur institute of iran, tehran, ir iran; genetics department, zanjan branch, islamic azad university, zanjan, ir iran mehri nikbin iranian liver charity, tehran, ir iran solmaz talebi department of biostatistics and epidemiology, tehran university of medical sciences, tehran, ir iran foozieh javadi department of hepatitis and aids, pasteur institute of iran, tehran, ir iran mohammad reza aghasadeghi department of hepatitis and aids, pasteur institute of iran, tehran, ir iran sanaz mahmazi genetics department, zanjan branch, islamic azad university, zanjan, ir iran

marwa khairy endemic medicine department and hepatology unit, faculty of medicine, cairo university, cairo, egypt rabab fouad endemic medicine department and hepatology unit, faculty of medicine, cairo university, cairo, egypt mahassen mabrouk endemic medicine department and hepatology unit, faculty of medicine, cairo university, cairo, egypt wafaa el-akel endemic medicine department and hepatology unit, faculty of medicine, cairo university, cairo, egypt abu bakr awad bioinformatic and statistic department, faculty of computer sciences, cairo university, cairo, egypt rabab salama endemic medicine department and hepatology unit, faculty of medicine, cairo university, cairo, egypt; endemic medicine and hepatology department, kasr el-aini faculty of medicine, cairo university, cairo, egypt. tel: +20-25262555, fax: +20-25326439