Class-Pi of glutathione s-transferases (GST-Pi) is the specific form of GSTs that are known to participate particularly in the mechanisms of resistance to drugs and carcinogens. This class of the enzyme is referred to as class-P or class-Pi or class π. The accepted terminology in this review article is class-Pi. In this article following a brief description of identified molecular forms of GSTs...

A series of mono-amide-functionalized pillar[5]arenes with different lengths of N-ω-aminoalkyl groups as the side chain on the rim were designed and synthesized, which all formed pseudo[1]rotaxanes in the crystal state. And these pseudo[1]rotaxanes could be transformed into [1]rotaxanes or open forms in the crystal state. In addition, they were also studied in solution by (1)H NMR spectroscopy.

A series of brominated mono-methano[60]fullerene malonate derivatives (two diads and one triad) are investigated for intramolecular and external heavy-atom effects on their fluorescence. Significant internal and external heavy-atom effects are observed in the three cases. It is shown that the internal effect doubles when going from the diads to the triad. In bromobenzene and in iodobenzene, the...

Glutathione transferases are enzymes involved in the detoxification against xenobiotics and noxious compounds. These catalyse a variety of reactions on many physiological xenobiotic compounds using glutathione as co-substrate. Moreover, inhibitors such enzymes. A wide array biosensors based have been developed for analysing compounds, well several devoted to detection quantification themselves....