introduction: toxigenic clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. the pathogenicity of c. difficile is related to toxins a&b.; children with cancer are at risk of developing c. difficile infection (cdi) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. recently, due to higher sensitivit...

The molecular approach to microbial pathogenesis has resulted in an impressive amount of data on bacterial virulence genes. Bacterial genome sequences rapidly add candidate virulence genes to electronic databases. The interpretation of this overwhelming information is obscured because every gene involved in pathogenicity is called a virulence gene, regardless of its function in the complex proc...

conclusions these results indicated that eaec strains isolated from iranian children with diarrhea were heterogeneous and showed high resistance rates against commonly used antibiotics, which was similar to that reported in studies performed in other countries. results significant percentage of local eaec strains carried the virulence plasmid genes and formed biofilms. in addition, these strain...

conclusions the trat gene and pai markers were highly prevalent among upec strains isolated from patients in kashan, iran; therefore these determinants could be used as targets for prophylactic interventions. also there was a high level of resistance against the antibiotics commonly used for urinary tract infection treatment. to reach better therapeutic outcomes, treatment regimens have to be m...

background shiga toxin-producing escherichia coli (stec) strains are considered as one of the most important widespread food-borne pathogens, which cause diarrhea and life threatening diseases, such as hemolytic uremic syndrome, in humans. more recently, the stec strains have also been incriminated to cause diarrhea and hemorrhagic colitis in calves; enteropathogenic e. coli (epec) also causes ...

Background: Salmonella is the most important source of food-borne infections around the world. Human salmonellosis is also found in fresh fruit and vegetable salads. Objective: to investigate detection of Salmonella spp.,  in Hamburger, Vegetable salads and Cream-filled pastries from factories, supermarkets, restaurants and local confectionery, Mazandaran, Iran, as well as, to assess their pat...

BACKGROUND: Colibacillosis is one of the most prevalentdiseases in the world that causes multimillion-dollar annuallosses. OBJECTIVES: In order to evaluate molecular epidemiologyof some virulence associated factors in Escherichia coli,isolated from poultry, the presence of iut A, iss, hly F, omp T, iroN, afa, sfa (S)and pap G (II) were investigated by multiplex PCRassay. METHODS: Two hundred th...

Although Aeromonas are common in aquatic habitats and have been marked as an arising risk to human health, some information dealing with antibiotic resistance profiles virulence factor genes involved pathogenicity understood. The objective of this study was evaluate the profile for A. sobria identify genes. isolates were collected from AL-Hillah River Babel near hospital swage water January unt...