inhibitor development is a lifelong challenge for patients with bleeding disorders who received replacement therapy. most commonly, inhibitor formation was observed in hemophilia a patients but patients with rare bleeding disorders (rbd) especially patients with deficiency of factor xiii (fxiii) and factor v (fv) can develop an inhibitor against exogenous factors. several factors considered as ...

Let (Xn,i)1≤i≤n,n∈N be a triangular array of row-wise stationary R-valued random variables. We use a “blocks method” to define clusters of extreme values: the rows of (Xn,i) are divided into mn blocks (Yn,j), and if a block contains at least one extreme value the block is considered to contain a cluster. The cluster starts at the first extreme value in the block and ends at the last one. The ma...

Background Equity and social inclusion for vulnerable groups in policy development processes and resulting documents remain a challenge globally. Most often, the marginalization of vulnerable groups is overlooked in both the planning and practice of health service delivery. Such marginalization may occur because authorities deem the targeting of those who already have better access to healthcar...

road traffic accident (rta) is a global burden of disease. more than 1.25 million people per year are killed by rtas. more than half of the fatalities strike vulnerable road users (e. g. pedestrians, skaters, cyclists and other non-protected road users). the ongoing challenge is to protect vulnerable road users (vru). as a vru is neither shielded by seatbelts or crumple zones nor by airbags, th...

background: vulnerable women are prone to sexually transmitted diseases (std) due to their special conditions and poor knowledge about these diseases in the society. therefore, the present study aimed to determine the vulnerable women’s self-care needs in knowledge, attitude and practice concerning std. methods: this is a cross-sectional-descriptive study conducted in 2014. the data collection ...