نتایج جستجو برای: vx

تعداد نتایج: 1146  

Journal: :Journal of neurochemistry 2002
Pierre-Gilles Henry Vincent Lebon Françoise Vaufrey Emmanuel Brouillet Philippe Hantraye Gilles Bloch

Inhibition of succinate dehydrogenase (SDH) by the mitochondrial toxin 3-nitropropionic acid (3-NP) has gained acceptance as an animal model of Huntington's disease. In this study 13C NMR spectroscopy was used to measure the tricarboxylic acid (TCA) cycle rate in the rat brain after 3-NP treatment. The time course of both glutamate C4 and C3 13C labelling was monitored in vivo during an infusio...

2006
C. A. Brevett G. W. Wagner

The nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl]methylphosphonothiolate) has been shown to decompose in contact with concrete surfaces. We have previously shown that 31P NMR can be employed to study 1) the adsorption of VX into concrete; 2) the decomposition kinetics; and 3) detect decomposition products. Recently reported results show a dramatic effect of the VX decomposition kinetics...

Journal: :Vaccine 2011
Phillip C Gauger Amy L Vincent Crystal L Loving Kelly M Lager Bruce H Janke Marcus E Kehrli James A Roth

Influenza is an economically important respiratory disease affecting swine world-wide with potential zoonotic implications. Genetic reassortment and drift has resulted in genetically and antigenically distinct swine influenza viruses (SIVs). Consequently, prevention of SIV infection is challenging due to the increased rate of genetic change and a potential lack of cross-protection between vacci...

2014
Amy B. Hall Dave Newsome Yuxin Wang Diane M. Boucher Brenda Eustace Yong Gu Brian Hare Mac A. Johnson Sean Milton Cheryl E. Murphy Darin Takemoto Crystal Tolman Mark Wood Peter Charlton Jean-Damien Charrier Brinley Furey Julian Golec Philip M. Reaper John R. Pollard

Platinum-based DNA-damaging chemotherapy is standard-of-care for most patients with lung cancer but outcomes remain poor. This has been attributed, in part, to the highly effective repair network known as the DNA-damage response (DDR). ATR kinase is a critical regulator of this pathway, and its inhibition has been shown to sensitize some cancer, but not normal, cells in vitro to DNA damaging ag...

Journal: :Journal of dental hygiene : JDH 2015
Hadeel M Ayoub Tara L Newcomb Gayle B McCombs Marshall Bonnie

PURPOSE This study compared the effectiveness of the VELscope® Vx versus visual and tactile intraoral examination in detecting oral lesions in an adult, high risk population. METHODS The pilot study compared the intra oral findings between 2 examination types. The sample was comprised of 30 participants who were addicted to either cigarettes or a dual addiction (cigarettes plus hookah). High ...

2014
Guido Veit Joseph Tan Ariel Roldan Walter E. Finkbeiner Gergely L. Lukacs A. S. Verkman

The most prevalent cystic fibrosis transmembrane conductance regulator (CFTR) mutation causing cystic fibrosis, DF508, impairs folding of nucleotide binding domain (NBD) 1 and stability of the interface between NBD1 and the membranespanning domains. The interfacial stability defect can be partially corrected by the investigational drug VX-809 (3-[6-[[[1-(2,2difluoro-1,3-benzodioxol-5-yl)cyclopr...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید چمران اهواز - دانشکده ریاضی و کامپیوتر 1393

می دانیم که حلقه ی توابع پیوسته ی حقیقی مقدار روی یک فضای تیخونوف x با( c(x نشان داده می شود. همچنین این گزاره شناخته شده است که هرگاه x وy دو فضای فشرده حقیقی بوده به طوری که (c(x و (c(y یکریخت باشند، آن گاه x و y همسان ریخت خواهند بود؛ یعنی، (c(x فضای x را معین می کند. محدودیت به فضاهای فشرده حقیقی از این حقیقت که (c(x و( c(vx یکریخت می باشند، ناشی می شود که فضای vx فشرده شده ی حقیقی هویت x...

Journal: :The Journal of organic chemistry 2009
Andrew M McAnoy Jilliarne Williams Martin R L Paine Michael L Rogers Stephen J Blanksby

The alkaline perhydrolysis of the nerve agent O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate (VX) was investigated by studying the ion-molecule reactions of HOO(-) with O,S-dimethyl methylphosphonothioate in a modified linear ion-trap mass spectrometer. In addition to simple proton transfer, two other abundant product ions are observed at m/z 125 and 109 corresponding to the S-met...

Journal: :Chemphyschem : a European journal of chemical physics and physical chemistry 2016
Juan Carlos Pérez-Flores Markus Hoelzel Flaviano García-Alvarado Alois Kuhn

Titanium-oxide-based materials are considered attractive and safe alternatives to carbonaceous anodes in Li-ion batteries. In particular, the ramsdellite form TiO2 (R) is known for its superior lithium-storage ability as the bulk material when compared with other titanates. In this work, we prepared V-doped lithium titanate ramsdellites with the formula Li0.5 Ti1-x Vx O2 (0≤x≤0.5) by a conventi...

Journal: :The American journal of physiology 1997
Michael K Hansen James M Krueger

The mechanism by which peripheral cytokines signal the central nervous system to elicit central manifestations of the acute phase response remains unknown. Recent evidence suggests that cytokines may signal the brain via the vagus nerve. To test this possibility, we examined sleep-wake activity and brain temperature (Tbr) after the intraperitoneal administration of saline or three doses (0.1, 0...

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