Precursor emission has been observed in a non-negligible fraction of gamma-ray bursts.The time gap between the precursor and the main burst extends in some case up to hundreds of seconds, such as in GRB041219A, GRB050820A and GRB060124. Both the origin of the precursor and the large value of the time gap are controversial. Here we investigate the maximum possible time gaps arising from the jet ...

The gamma-tubulin small complex (gamma-TuSC) is an evolutionarily conserved heterotetramer essential for microtubule nucleation. We have determined the structure of the Saccharomyces cerevisiae gamma-TuSC at 25-A resolution by electron microscopy. gamma-TuSC is Y-shaped, with an elongated body connected to two arms. Gold labeling showed that the two gamma-tubulins are located in lobes at the en...

Microtubules are hollow polymers of alphabeta-tubulin that show GTP-dependent assembly dynamics and comprise a critical part of the eukaryotic cytoskeleton. Initiation of new microtubules in vivo requires gamma-tubulin, organized as an oligomer within the 2.2-MDa gamma-tubulin ring complex (gamma-TuRC) of higher eukaryotes. Structural insight is lacking regarding gamma-tubulin, its oligomerizat...

Effects of quinidine, disopyramide, and procainamide on the acetylcholine (ACh)-induced K+ channel current were examined in single atrial cells, using the tight-seal, whole-cell clamp technique. The pipette solution contained guanosine-5'-triphosphate (GTP) or guanosine-5'-O-(3-thiotriphosphate) (GTP-gamma S, a nonhydrolysable GTP analogue). In GTP-loaded cells, not only ACh but also adenosine ...

Performance of a free-space optical communication system is influenced by atmospheric turbulence which degrades signal transmission quality. A gamma–gamma channel model employed to characterise this under weak-to-strong conditions. The proposed dual diffuser modulation using subtraction dual-wavelength concept combined with phase screen improve transmission. Its performances are compared conven...

To illustrate the standard candle property of gamma-ray pulsars (and also to thereby confirm the recent first-principle calculation of pulsar gamma-ray emission), we “measure”, via the lightcurve fitting, three distances and one moment of inertia of some weak pulsars. We are not sure what the three distances are good for, but the measurement of the moment of inertia must be of interest for nucl...

More than a dozen blazars are known to be emitters of multi-TeV gamma rays, often with strong and rapid flaring activity. By interacting with photons of the cosmic microwave and infrared backgrounds, these gamma rays inevitably produce electron-positron pairs, which in turn radiate secondary inverse Compton gamma rays in the GeV-TeV range with a characteristic time delay that depends on the pro...

Improving our understanding of the nuclear properties high-Eddington ratio ($\lambda_\mathrm{Edd}$) active galactic nuclei (AGN) is necessary since bulk X-ray spectroscopic studies have been focused on low-Eddington AGN. We present here spectral analysis 14 radio-quiet, $\lambda_\mathrm{Edd}\gtrsim1$ AGN at $0.4\leq z \leq 0.75$, observed with XMM-Newton. Optical/UV data from simultaneous Optic...

Macaque frontal eye fields (FEF) and the lateral intraparietal area (LIP) are high-level oculomotor control centers that have been implicated in the allocation of spatial attention. Electrical microstimulation of macaque FEF elicits functional magnetic resonance imaging (fMRI) activations in area LIP, but no study has yet investigated the effect of FEF microstimulation on LIP at the single-cell...