Studies light emitting devices based on MEHPPV and then performed electrical characterization over these. It has been found that light emitting efficiency of basic PLED viz. ITO/ MEHPPV/AI can be improved if added a buffer layer of Lif in between polymer and Al. This increased efficiency can be attributed to the lowering of potential barrier at AI cathode due to the presence of LiF buffer layer...

Ibuprofen is metabolized to chemically reactive acyl glucuronide and S-acyl-CoA metabolites that are proposed to transacylate glutathione (GSH) forming ibuprofen-S-acyl-GSH (I-SG) in vivo. Herein, we report the detection of novel metabolites of ibuprofen, namely ibuprofen-N-acyl-cysteinylglycine (I-N-CG), ibuprofenN-acyl-cysteine (I-N-C), and the mercapturic acid conjugate, ibuprofen-S-acyl-N-a...

Kainate receptors (KARs), a family of ionotropic glutamate receptors, are widely expressed in the central nervous system and are critically involved in synaptic transmission. KAR activation is influenced by metabotropic glutamate receptor (mGlu) signaling, but the underlying mechanisms are not understood. We undertook studies to examine how mGlu modulation affects activation of KARs. Confocal i...

An autoimmune etiology has been proposed for a variety of movement disorders, making the detection of autoantibodies a high investigative priority. Recognizing the existence of different methodologic approaches to identify these antibodies, we sought to investigate the effects of tissue preparation, antibody selection, and Western immunoblot detection methods on outcome. ELISA and immunoblottin...

Hormones are agents of biological coordination that circulate systemically to signal diverse cells and tissues, thereby influencing nearly all aspects of the phenotype, including behavior, morphology, physiology, and life history. Hormonal phenotypes can be both heritable and subject to natural selection (Bonier et al. 2009; McGlothlin et al. 2010; Ouyang et al. 2011; Pavitt et al. 2014; Cox et...

prescriptions about the timing of first sex, vary to a great extent according to a youth’s gender and ethnicity.8 Most research has concentrated on females, partly because national fertility studies interview only females and because of the historical interest in teenage pregnancy. However, studies that have included both males and females have consistently shown gender differences in the age a...