BACKGROUND The aim of the present study was to evaluate the accuracy of two approaches using magnetic resonance imaging (MRI) or combined ultrasonography (US) and anti-cyclic citrullinated peptide antibody (ACPA) for diagnosis and classification of individuals with established rheumatoid arthritis (RA). METHODS In 53 individuals from a population-based, cross-sectional study, historic fulfilm...

OBJECTIVES To investigate the expression and activation of mitogen-activated protein kinases in patients with early arthritis who are disease-modifying antirheumatic drug (DMARD) naïve. METHODS A total of 50 patients with early arthritis who were DMARD naïve (disease duration <1 year) were prospectively followed and diagnosed at baseline and after 2 years for undifferentiated arthritis (UA), ...

OBJECTIVE To evaluate the ability of the widely used ACR set of criteria (both list and tree format) to diagnose RA compared with expert opinion according to disease duration. METHODS A systematic literature review was conducted in PubMed and Embase databases. All articles reporting the prevalence of RA according to ACR criteria and expert opinion in cohorts of early (<1 year duration) or est...

OBJECTIVES It has been shown in early arthritis cohorts that the 2010 ACR/EULAR criteria for rheumatoid arthritis (RA) enable an earlier diagnosis, perhaps at the cost of a somewhat more heterogeneous patient population. We describe the features of synovial inflammation in RA patients classified according to these new criteria. METHODS At baseline, synovial tissue biopsy samples were obtained...

OBJECTIVE Early identification of patients with rheumatoid arthritis (RA) is essential to allow the prompt institution of therapy. The 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria, which replace the 1987 classification criteria, have been developed to facilitate such identification in patients with newly presenting inflammatory a...

OBJECTIVE Early recognition and treatment of RA is associated with an improved outcome. The 2010 ACR/EULAR criteria for RA identify RA patients earlier than the 1987 ACR criteria. Nevertheless, we recently observed that 24% of the 2010 unclassified arthritis (UA) patients develop RA during follow-up. Here we studied this frequency in other cohorts and evaluated the prognostic accuracy of ACPA a...

The ACR's Mammography Accreditation Program has been helping facilities improve the quality of mammography through peer review and professional feedback since 1987. Initially conceived as a voluntary program, accreditation became mandatory when the Mammography Quality Standards Act (MQSA) of 1992 required all U.S. mammography facilities to become accredited and certified by October 1, 1994. Cur...

The need for early initiation of treatment in rheumatoid arthritis (RA) has been established. The 1987 RA classification criteria are not suitable for this strategy. Therefore, as a collaboration of ACR and EULAR, new classification criteria for RA were published in 2010. Several studies assessed agreement between 1987 and 2010 criteria and the potential source of discordance. This review will ...