نتایج جستجو برای: 85 peptide

تعداد نتایج: 245786  

Journal: :iranian journal of cancer prevention 0
abbas zare mirakabadi department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran. saeed moradhaseli 1- department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran. 2- department of biochemistry, faculty of basic sciences, payame noor university, tehran, iran.

background: current anti-cancer drug therapy results in systemic side effects due to non-specific uptake by normal healthy noncancerous tissues. to alleviate this difficulty, many attempts have been devoted to the development of new delivery systems such as polymeric nanoparticles (nps). in this study, we prepared icd-85 nps based on sodium alginate and analyzed the cytotoxic activity of icd-85...

2017

The concept of school sport on which we are basing our experience is set in the Historical Territory of Bizkaia (Basque Country, Spain) and this is regulated by Bizkaia’s Diputación Foral (Provincial Council), governed by the regional regulations of the Basque Government. This government takes the view that School Sport covers sport activities at teaching centres outside actual school teaching ...

2015
Slavica B. Ilić Sandra S. Konstantinović Gordana Gojgić-Cvijović Dragiša S. Savić Vlada B. Veljković

A media consisting of isatin-Schiff bases and its inclusion complexes with β-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and azalomycine B by Streptomyces hygroscopicus CH-7. The media with β-cyclodextrine inclusion complex of isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 493 μg/cm for Hexaene H-85 and 191 μg/cm for azalom...

1998
Chen-Chung Yang Hong-Lin Chan

....................................................................................................................................................... 79 INTRODUCTION ................................................................................................................................................. 80 NUMBER OF ANTIGENIC DETERMINANTS ON β1-Bgt ........................................

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Joel N H Stern Zsolt Illés Jayagopala Reddy Derin B Keskin Masha Fridkis-Hareli Vijay K Kuchroo Jack L Strominger

Myelin basic protein (MBP) is a major candidate autoantigen in multiple sclerosis (MS). Its immunodominant epitope, MBP 85-99, forms a complex with human leukocyte antigen (HLA)-DR2 with which multiple sclerosis is genetically associated. Copolymer 1 (Copaxone), a random amino acid copolymer [poly (Y,E,A,K)n] as well as two modified synthetic copolymers [poly (F,Y,A,K)n and poly (V,W,A,K)n] als...

Journal: :The Journal of Experimental Medicine 1986
N Shastri G Gammon A Miller E E Sercarz

Ak- or Ek-restricted T cells, generated by immunization with a 23-amino-acid peptide of hen egg-white lysozyme (amino acid 74-96), showed a strict correlation between the minimal peptide determinant recognized and the Ia molecule restricting recognition. All Ak-restricted clones obtained from six independently derived lines recognized determinants contained within peptides 74-86, while Ek-restr...

Abbas Zare Mirakabadi Mostafa Erfani Reza Bagheri Seyed Pezhman Shirmardi, Zahra Pakdin Parizi

Introduction: Many molecules can be labeled by iodine. Some of labeled substances are used for investigations of cancer treatment, biodistribution study in body, receptor binding, secrete pathway etc. Peptides are biomolecules and can be labeled by 131Iodine. ICD- 85 is a tri-peptide derived from Iranian brown snake venom and scorpion venom. This tri-peptide treats cancer by i...

Journal: :Journal of immunology 2008
Angelos D Gritzapis Ioannis F Voutsas Eftychia Lekka Nikolaos Tsavaris Ioannis Missitzis Panagiota Sotiropoulou Sonia Perez Michael Papamichail Constantin N Baxevanis

HER-2/neu oncoprotein is overexpressed in a variety of human tumors and is associated with aggressive disease. Immunogenic HER-2/neu CTL epitopes have been used as vaccines for the treatment of HER-2/neu positive malignancies with limited success. By applying prediction algorithms for MHC class I ligands and proteosomal cleavages, in this study, we describe the identification of HER-2/neu decam...

Journal: :Molecules 2017
John A Karas Marc-Antoine Sani Frances Separovic

The chemical synthesis of an 85 residue analogue of the pore-forming protein, Equinatoxin II (EqtII), was achieved. Peptide precursors with over 40 residues were assembled by solid phase synthesis. The EqtII(1-46) fragment was modified to the reactive C-terminal thioester and native chemical ligation was performed with the A47C mutated EqtII(47-85) peptide to form the EqtII(1-85) analogue. Circ...

Journal: :The Journal of Experimental Medicine 1998
Anna Lobell Robert Weissert Maria K. Storch Cecilia Svanholm Katrien L. de Graaf Hans Lassmann Roland Andersson Tomas Olsson Hans Wigzell

We explore here if vaccination with DNA encoding an autoantigenic peptide can suppress autoimmune disease. For this purpose we used experimental autoimmune encephalomyelitis (EAE), which is an autoaggressive disease in the central nervous system and an animal model for multiple sclerosis. Lewis rats were vaccinated with DNA encoding an encephalitogenic T cell epitope, guinea pig myelin basic pr...

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