OBJECTIVE Calcium fluoride deposit during fluoride application. Uptake and retention of fluoride by saliva depends generally on the concentration of calcium. In this study, the effect of calcium pre-rinse on salivary fluoride concentration after a 900 ppm fluoride mouthwash was investigated. MATERIALS AND METHODS This cross-over double-blind randomized clinical trial was conducted in a girls'...

To prove a direct relationship between the quasi-static electric field disturbances and seismic activity is a difficult, but actual task of the modern ionosphere physics. This paper presents new results on the processing and analysis of the quasi-static electric field in the upper ionosphere (h=800–900 km) observed from the satellite INTERCOSMOS-BULGARIA-1300 over earthquakes’ source regions (s...

Using in vitro drug sensitivity data coupled with Affymetrix microarray data, we developed gene expression signatures that predict sensitivity to individual chemotherapeutic drugs. Each signature was validated with response data from an independent set of cell line studies. We further show that many of these signatures can accurately predict clinical response in individuals treated with these d...

Brain metastases are a major cause of mortality in patients with advanced melanoma. Adequate brain distribution of targeted agents for melanoma will be critical for treatment success. Recently, improvement in overall survival led to US Food and Drug Administration (FDA) approval of the v-raf murine sarcoma viral oncogene homolog B (BRAF) inhibitors, vemurafenib and dabrafenib, and the mitogenac...

Abstract A period that lasted from 900-1300 AD has been known as the Medieval Climate Anomaly. This indicated warming of earth’s temperature. However, this phenomenon is still subject debate today, whether global or regional warming. Several studies concluded warm a and an important period, although external forcing mainly similar to present day. climate archives Indonesia i.e. lake sediment, m...

The need for structural materials with high-temperature strength and oxidation resistance coupled with adequate lower-temperature toughness for potential use at temperatures above ,1000 8C has remained a persistent challenge in materials science. In this work, one promising class of intermetallic alloys is examined, namely, boron-containing molybdenum silicides, with compositions in the range M...

Hydroxyapatite (HA) is a widely studied biomaterial for its similar chemical composition to bone and its osteoconductive properties. The crystal structure of HA is flexible, allowing for a wide range of substitutions which can alter bioactivity, biodegradation, and mechanical properties of the substituted apatite. The thermal stability of a substituted apatite is an indication of its biodegrada...

t-Butyl alcohol is widely used in the manufacture of perfumes and a variety of cosmetics. It is also used as a raw material in the production of isobutylene, which may be used to produce methyl tertiary butyl ether, a common gasoline additive, or to produce butyl elastomers used in the production of automobile tires. The National Cancer Institute nominated t-butyl alcohol to the NTP for study a...