introduction: angiogenesis, the process of new blood vessel formation from pre-existing vessels, has important physiological roles in embryonic development, female reproduction cycle, and wound healing. it is also crucial for pathological processes in several diseases especially tumor growth and metastasis. thereby, inhibition of angiogenesis as an addition to the conventional therapies such as...

background: anti-angiogenic therapy is a crucial step in cancer treatment. the discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. because little data correlated to the pro- and anti-angiogenic efficacies of ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...

objective: acorus calamus (a. calamus) has been used as a medicinal plant in asia for its effects on digestive system for the last 2000 years. to investigate the anti-cancer activity of rhizome of a. calamus, the ethanolic and methanolic extracts and essential oil of the rhizome were prepared and their effects were assessed on human gastric cancer cell line (ags). materials and methods: the via...

background and objectives: datura innoxiamilleris one of the two species of datura (solanaceae) which grow in iran. there are many reports of the biological activities of datura and in the present study the ability of datura innoxia for inhibiting angiogenesis was evaluated. methods: the methanol extract and petroleum ether, chloroform and methanol fractions of datura innoxia flowers were obtai...

Background and objectives: Datura innoxiaMilleris one of the two species of Datura (Solanaceae) which grow in Iran. There are many reports of the biological activities of Datura and in the present study the ability of Datura innoxia for inhibiting angiogenesis was evaluated. Methods: The methanol extract and petroleum ether, ...

background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...

angiogenesis which is the recruitment of new blood vessels is a critical process in several chronic diseases and is an essential component of tumor or cancer progression. development of therapies aimed at inhibiting the angiogenesis, in combination with classical anti-cancer therapies, is among the most intensively studied approaches to treat the cancer. in this study the effect of chlordiazepo...

Background and objectives: Angiogenesis is essential for tumor survival. Inhibiting angiogenesis could be a mechanism for hindering tumor development. Numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. In the present study, Crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesi...