Objective(s): Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary artery disease (CAD) risk. The aim of this study was to study the association of the Apolipoprotein E genotypes with coronary artery disease in the Iranian population.   Materials and Methods: The Apolipoprotein E genotype in DNA samples extracted from 66 CAD+ patients and 61 control s...

background: alzheimer's disease as a neurodegenerative disorder is the commonest type of dementia. a growing number of genes have been reported as the risk factors, which increase the susceptibility to alzheimer's disease. apolipoprotein e ( apoe) , which its ε4 allele has been reported as a risk factor in late onset alzheimer's disease (ad), is the main cholesterol carrier in the brain. the ma...

objective(s): apolipoprotein e genotype (apoe) polymorphism affects lipid levels and coronary artery disease (cad) risk. the aim of this study was to study the association of the apolipoprotein e genotypes with coronary artery disease in the iranian population.   materials and methods: the apolipoprotein e genotype in dna samples extracted from 66 cad+ patients and 61 control subjects by restri...

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Diabetes is one of the most common metabolic diseases in the world. Vitamin E reduces protein glycation and improves insulin sensitivity, while cumin is effective in remission of diabetes. Therefore this study was designed to evaluate the effects of vitamin E and cumin essential oil, on the blood level of leptin,glycosylated hemoglobin (HbA1C) and also on lipid profile in diabetic patients.In t...

PURPOSE The inheritance of specific apolipoprotein E allelles has been linked to atherosclerosis, Alzheimer disease, and, most recently, to the incidence of age-related macular degeneration. Apolipoprotein E is a common component of the extracellular plaques and deposits characteristic of these disorders, including drusen, which are a hallmark of age-related macular degeneration. Accordingly, w...

Alzheimer's disease (AD) is a complex disorder with a clear genetic component. Three genes have been identified as the cause of early onset familial AD (EOAD). The most common form of the disease, late onset Alzheimer's disease (LOAD), is, however, a sporadic one presenting itself in later stages of life. The genetic component of this late onset form of AD has been the target of a large number ...