in most cases atherosclerosis is the underlying cause of vascular diseases, including heart disease and stroke. it is believed that endothelial injury is the earliest change in the artery wall and that this precedes the formation of lesions of atherosclerosis. recent developments in the field of atherosclerosis have led to a renewed interest in the recognition of the parameter of time in the at...

atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. disturbed adiponectin actions through its receptor, (adipor1 and adipor2) may be involved in atheros...

In most cases atherosclerosis is the underlying cause of vascular diseases, including heart disease and stroke. It is believed that endothelial injury is the earliest change in the artery wall and that this precedes the formation of lesions of atherosclerosis. Recent developments in the field of atherosclerosis have led to a renewed interest in the recognition of the parameter of time in the at...

background: inflammation is involved in development, progression, and complications of atherosclerotic disease. clinical studies have indicated that the level of monocyte chemoattractant protein 1 (mcp-1), il-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. experimental studies have shown pentoxifylline (ptx) reduces these ...

background: in this study, we used a new computerized analytical method for the measurement of the endothelial function in sequential ultrasound images and compared it with histological studies, using the abdominal aorta in normal and atherosclerotic rabbits. methods: six rabbits received a standard rabbit chow as the normal group and the other 6 rabbits were fed a high cholesterol diet for fou...

background: according to the angiographic findings, 3%-8% of atherosclerotic coronary artery patients suffer from coronary artery ectasia (cae). we conducted this study to estimate the prevalence of cae among patients who underwent angiography and compared this group with those patients without cae and atherosclerosis in terms of common coronary heart disease (chd) risk factors. methods : this ...

background adiponectin is an adipose tissue-derived protein with anti-inflammatory properties. statins are a class of cholesterol-lowering drugs, widely used for treatment of cardiovascular diseases. objectives in the current study, we aimed to assess the effects of simvastatin on serum levels of adiponectin in patients with dyslipidemia, recruited from ghaem hospital, mashhad, iran. materials ...

background: atherosclerosis is one of the most important cardiovascular diseases that involve vessels through the development of fatty streaks and plaques. plant?based compounds can help treat or prevent atherosclerosis through affecting the involved factors. the main purpose of this review article is to investigate and introduce medicinal plants and their potential activities regarding antioxi...