Of 396 Pseudomonas aeruginosa strains isolated from hospital sewage, the blaSPM-1 gene was confirmed in nine. This is the first report of environmental P. aeruginosa strains carrying the blaSPM-1 gene in Brazil. The carbapenem resistance, already disseminated among clinical isolates, has been detected among environmental isolates.

A Pseudomonas aeruginosa é uma bactéria oportunista, considerada um dos principais agentes de infecção nosocomial em hospitais associada múltipla resistência a antimicrobianos. Em animais, principalmente cães, otite enfermidade grande incidência associado P. aeruginosa. ocorrência isolados multirresistentes metalo beta lactamase com presença genes blaIMP-1, blaVIM-2, blaSPM-1 e blaNDM-1 tem sid...

We read with interest the article by Doi et al. (2) suggesting that the coproduction of the metallo-lactamase SPM-1 and the RmtD 16S RNA methylase is highly prevalent among imipenem-resistant Pseudomonas aeruginosa isolates from Brazil. SPM-1 is widespread among Brazilian carbapenem-resistant P. aeruginosa isolates, and isolates carrying blaSPM-1 have been observed in distinct regions of this c...

We read with interest the article by Doi et al. (2) suggesting that the coproduction of the metallo-lactamase SPM-1 and the RmtD 16S RNA methylase is highly prevalent among imipenem-resistant Pseudomonas aeruginosa isolates from Brazil. SPM-1 is widespread among Brazilian carbapenem-resistant P. aeruginosa isolates, and isolates carrying blaSPM-1 have been observed in distinct regions of this c...

igh-level carbapenem resistance in Pseudomonas aeruginosa s a recognized public health problem. Metallo-lactamase MBL) is one of the most common resistance mechanisms n these microorganisms. The gene blaSPM-1, which is the ost frequent metallo-lactamase gene in Brazil, was first escribed in 20021 and has been found in different regions.2 ntil now there has been no record of carbapenemase enzyme...

INTRODUCTION The emergence of carbapenem resistance mechanisms in Pseudomonas aeruginosa has been outstanding due to the wide spectrum of antimicrobial degradation of these bacteria, reducing of therapeutic options. METHODS Sixty-one clinical strains of P. aeruginosa isolated from five public hospitals in Recife, Pernambuco, Brazil, were examined between 2006 and 2010, aiming of evaluating th...

Methods: The studied population included 59 MDRAB strains previously genotyped by PFGE and multilocus sequence typing. The search for the ADC (blaADC), CHO (blaOXA-51-like, blaOXA-23-like, blaOXA-40-like and blaOXA-58-like) and MBL (blaIMP, blaVIM, blaSIM-1, blaGIM-1, blaSPM-1 and blaNDM-1) genes, and for the ISs (ISAba1, ISAba2, ISAba3, ISAba4 and IS18) was done by PCR assays. The phenotypic p...