abstract background and objective: iranian traditional medicine (itm) has a long history in the prevention and treatment of diseases. clinical uses, side effects, and toxic effects of many singular and compounds were known to scientists of itm and articular books on toxicology and detoxification of drugs has been written by scientists, but their measurement tools to evaluate chronic toxicity of...

This paper provides a review of natural Chinese drug products, including phytochemic compounds, medicinal herbs and multi-component herbal formulae, that have been reported to possess hypoglycemic activity with mechanisms for antidiabetic action. Along with a great number of combination formulae, ∼ 187 different Chinese medicinal herbs are clinically applied to treat diabetes mellitus and its c...

Pregnane and Xenobiotic Receptor (PXR), a vital xenosensor, acts as master regulator of phase-I (cytochrome P450) and phase-II enzymes (glutathione S-transferases, sulfotransferases, and uridine 5’-diphosphate glucuronosyltransferases) as well as several drug transporters (multi-drug resistance protein, and multidrug resistance-associated protein). PXR can bind to a variety of chemically distin...

conclusions the results of this study suggest that e. hebecarpa extracts can be used to inhibit the planktonic and biofilm forms of these selected bacteria. objectives in an effort to combat these industrial and medical bacterial biofilm problems, our study aims to determine the antimicrobial effect of euphorbia hebecarpa. materials and methods the inhibition efficiency of alcoholic extracts on...

Two concepts involving natural products were proposed and demonstrated in this paper. (1) Natural product libraries (e.g. herbal extract) are not perfect for bioactivity screening because of the vast complexity of compound compositions, and thus a library reconstruction procedure is necessary before screening. (2) The traditional mode of "screening single compound" could be improved to "screeni...

Background Malaria accounts for 60% of outpatient visits in Nigeria. The aim of the study was to assess the knowledge of malaria and its treatment practices in Enugu state, Nigeria.   Methods Qualitative data was collected through the use of focus group discussions (FGDs), from six villages three each from urban and rural areas of Enugu state, Nigeria. A total of 18 FGDs involving 189 participa...

Traditional Chinese medicine (TCM) is a holistic approach to health that attempts to bring the body, mind and spirit into harmony. TCM is an essential part of the healthcare system in several Asian countries, and is considered a complementary or alternative medical system in most Western countries. An integration of the traditional Chinese and Western systems of medicine has begun in multiple m...

Herbal ingredients in a Chinese fufang prescription are often replaced by one or several other herbal combinations. As there have been very few Chinese herbal patent infringement cases, it is still unclear how the Doctrine of Equivalents should be applied to determine the scope of 'equivalents' in Chinese fufang prescriptions. Case law principles from cases in other technical areas such as chem...

ABSTRACT ABSTRACT Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL)...