نتایج جستجو برای: Crude venom

تعداد نتایج: 47082  

A. Akbari A. Hedayat H. Rabiei H. Zolfagharian N. Mohammadpour Sh. Teimorzadeh

Conventional treatment of Naja naja oxiana (NNO) envenoming requires large volumes of equine antivenin raised against NNO crude venom. The poor efficiency of this antivenin is assumed to be due to the high molecular weight non-toxic proteins, a strong immunogen, present in the crude venom. These proteins cause depression of antibody formation against the low molecular weight toxic components of...

Journal: :archives of razi institute 2016
h. zolfagharian n. mohammadpour a. hedayat h. rabiei a. akbari

conventional treatment of naja naja oxiana (nno) envenoming requires large volumes of equine antivenin raised against nno crude venom. the poor efficiency of this antivenin is assumed to be due to the high molecular weight non-toxic proteins, a strong immunogen, present in the crude venom. these proteins cause depression of antibody formation against the low molecular weight toxic components of...

Background and purpose: Vipera lebetina lives in different areas in Iran, and its venom contains a variety of proteins with coagulant and anticoagulant activities. Fibrinolytic enzymes could have a therapeutic role in dissolution of blood clots, so, this study aimed at separating the venom components of Iranian V. lebetina and detecting its anticoagulant activity. Materials and methods: In thi...

ژورنال: کومش 2022

Introduction: Infectious diseases, mainly caused by bacterial agents, are one of the most common causes of death worldwide. A significant number of these agents have been resistant to one or more antibiotics; some of them are multi-drug resistant and others are extensively drug resistant. Various antimicrobial and anticancer compounds have been reported from the venom of various species of scor...

2016
Marina G. Ferreira Clara G. Duarte Maira S. Oliveira Karen L. P. Castro Maílson S. Teixeira Lílian P. G. Reis José A. Zambrano Evanguedes Kalapothakis Ana Flávia R. M. Michel Benito Soto-Blanco Carlos Chávez-Olórtegui Marília M. Melo

Specific anti-venom used to treat scorpion envenomation is usually obtained from horses after hyperimmunization with crude scorpion venom. However, immunized animals often become ill because of the toxic effects of the immunogens used. This study was conducted to evaluate the toxic and immunogenic activities of crude and detoxified Tityus serrulatus (Ts) venom in sheep during the production of ...

Journal: :the iranian journal of pharmaceutical research 0
hossein vatanpour 1-department of toxicology and pharmacology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2-razi vaccine, serum production and research institute, karaj, iran. farhad ahmadi 1-department of toxicology and pharmacology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2-student research committee, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. abbas zare mirakabadi razi vaccine, serum production and research institute, karaj, iran. amir jalali department of toxicology and pharmacology , school of pharmacy, toxicology research center, ahvaz jundishapur university of medical sciences, ahvaz, iran.

buthotus schach finally, according to our results venom as well as fractions f4 and f6 act mostly prejunctionally on ach release. more attempt is carrying out to study their effects on ion channel activities. is one of the most dangerous scorpions in tropical part of iran. the effects of its crude venom at 1, 3, 10 µg/ml and its obtained fractions by gel filtrations were investigated on neuromu...

2014
Giuseppe Bruschetta Daniela Impellizzeri Rossana Morabito Angela Marino Akbar Ahmad Nunziacarla Spanò Giuseppa La Spada Salvatore Cuzzocrea Emanuela Esposito

Cnidarian toxins represent a rich source of biologically active compounds. Since they may act via oxidative stress events, the aim of the present study was to verify whether crude venom, extracted from the jellyfish Pelagia noctiluca, elicits inflammation and oxidative stress processes, known to be mediated by Reactive Oxygen Species (ROS) production, in rats. In a first set of experiments, the...

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...

Journal: :iranian journal of pharmaceutical research 0
maryam kakanj toxicology and pharmacology department, school of pharmacy, medical science university of shahid beheshti, tehran, iran. hossein vatanpour toxicol. & pharmacol., dep. school of pharmacy, med. sci. uni. of shahid beheshti, tehran, iran mahmoud ghazi-khansari pharmacology dep., school of medicine, tehran university of medical sciences, tehran, iran abbas zare mirakabadi venomous animals and antivenom production dep., razi vaccine and serum research institute, karaj, iran bahram daraei - toxicology dep., faculty of medical sciences, tarbiat modares university, tehran, iran

objective: envenomation by heamotoxic snakes constituted a critical health occurrence in the world. bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. it is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. this study was to evaluate the...

2015
Mariana Ferreira Silva Caroline Martins Mota Vanessa dos Santos Miranda Amanda de Oliveira Cunha Maraísa Cristina Silva Karinne Spirandelli Carvalho Naves Fábio de Oliveira Deise Aparecida de Oliveira Silva Tiago Wilson Patriarca Mineo Fernanda Maria Santiago Glenn F. King

Hymenoptera venoms constitute an interesting source of natural toxins that may lead to the development of novel therapeutic agents. The present study investigated the enzymatic and biological characteristics of the crude venom of the ant Odontomachus bauri. Its crude venom presents several protein bands, with higher staining for six proteins with gelatinolytic activity (17, 20, 26, 29, 43 and 4...

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