نتایج جستجو برای: Cyclophosphamide drug
تعداد نتایج: 611229 فیلتر نتایج به سال:
stabilities and quantum molecular descriptors of cyclophoshphamide (an anticancer drug)-functionalized (8,0) zigzag and (4,4) armchair carbon nanotubes (cnts) complexes in water were studied using density functional theory (dft) calculations. two attachments namely the sidewall- and tip-attachments are considered for the model constructions. calculations of the total electronic energy (et) and ...
Background & Objectives: Cyclophosphamide (with the brand name of Endoxana) is an anti-cancer drug used in chemotherapy. The side effects of this drug include anoretic, nausea, decrease in genital gland function, creating amenorrhea, azoospermia and oligospermia. Garlic has been used throughout history as a medicinal drug and a beneficial spice in cooking. The beneficial effects of garlic which...
Background & Objective: Cyclophosphamide is an antineoplastic drug that has many clinical uses in cancer treatment, but it has toxic effects due to creation of free radicals. In this study, the effects of curcumin" as an antioxidant drug” on liver tissue was investigated. Materials & methods: 50 wistar adult male rats were selected randomly and were divided in to five groups including co...
Background: Cyclophosphamide as an alkalizing and cytotoxic agent contributes in treatment of different kinds of cancer. It can pass the blood-brain barrier. Linking two strains of DNA in cell nucleus and breaking the inner and outer strain linkages and inhibiting RNA synthesis and as a consequence, inhibiting protein synthesis, cyclophosphamide demonstrates severe pharmacological side effects ...
the study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. goat liver and white new zealand rabbit were used as lipid source for the models. lipid peroxidation study was performed by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide con...
Cyclophosphamide, a chemotherapeutic and immunosuppressive drug, has been linked to problems after bone marrow transplantation in the past. More recently, it demonstrated that cardiotoxicity limits dose of cyclophosphamide, cardiology is receiving more attention. Though exact mechanism cyclophosphamide-induced unknown, oxidative nitrative stress are suspected play role. As result, focus this re...
Introduction and Objective: liver is an important body organ without which life is impossible. Cyclophosphamide is an alkylating agent widely used as an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. The present study aimed to find a suitable antioxidant and examine the effect of vitamin E and selenium on reducing the side effects of cyclophosphamide on liver as a vit...
Background & Aims: Cyclophosphamide is an anticancer drug that, despite its many clinical applications, has toxic effects through production of free radicals on body. The aim of this study was to evaluate the protective effects of N-acetylcysteine in the liver tissue of rats treated with cyclophosphamide Materials & Methods: Twenty-one adult female Wistar rats were randomly divided into 3 grou...
Introduction and Objective: liver is an important body organ without which life is impossible. Cyclophosphamide is an alkylating agent widely used as an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. The present study aimed to find a suitable antioxidant and examine the effect of vitamin E and selenium on reducing the side effects of cyclophosphamide on liver as a vit...
introduction and objective: liver is an important body organ without which life is impossible. cyclophosphamide is an alkylating agent widely used as an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. the present study aimed to find a suitable antioxidant and examine the effect of vitamin e and selenium on reducing the side effects of cyclophosphamide on liver as a vital organ....
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