The dynamic strain aging (DSA) behavior was investigated in GH4169 alloy during tensile deforming with electric-pulse current (EPC) at 750 °C. results show that DSA is restrained the when deformed 40 Hz-EPC. size of γ″ phase inner grains increases obviously and δ facilitated to precipitate on grain boundary applied EPC, due promotion effect EPC diffusion segregation atoms. Transmission electron...

OBJECTIVE Endothelial progenitor cells (EPC) in one study group is not the same as EPC in other investigators, suggesting that EPC is not a single type of cell population. In this study, we tried to demonstrate the heterogeneity of EPC. METHODS AND RESULTS We cultured total mononuclear cells from human peripheral blood to get two types of EPC sequentially from the same donors. We called them ...

The precise and conceptual insight of circulating endothelial progenitor cell (EPC) kinetics is hampered by the absence of an assay system capable of evaluating the EPC differentiation cascade. An assay system for EPC colony formation was developed to delineate circulating EPC differentiation. EPC colony-forming assay using semisolid medium and single or bulk CD133(+) cells from umbilical cord ...

INTRODUCTION Previously, we demonstrated that children with active systemic vasculitis (SV) have higher circulating CD34 + CD133 + KDR+ endothelial progenitor cells (EPC); the function of these EPCs, and their relationship with disease activity in vasculitis remains largely unexplored. We hypothesized that although EPC numbers are higher, EPC function is impaired in active SV of the young. The ...

engineering – procurement and construction (epc) contract is one of the current contracts in the today world. when governmental sector trends to use the expertise of domestic or foreign private in engineering and construction of infrastructural projects, finds epc contract as a suitable legal frame. in this article, we have tried to discuss about the most important legal aspects of this kind of...

Endothelial progenitor cells (EPC) are bone-marrow derived circulating cells participating in angiogenesis and vascular homeostasis. Reduced numbers of circulating EPC are observed in patients with various cardiovascular diseases and are related to an increased risk for future cardiovascular events and death. Little is known about functional changes. The aim of this thesis was to study the func...

BACKGROUND EPC number and functionality are assumed to reflect the endogenous vascular repair capacity with the EPC pool declining in higher ages and being exhausted by unfavorable life-style and risk factors. This intriguing and clinically highly relevant concept, however, has so far been derived from small case-control studies and patient series. METHODOLOGY AND PRINCIPLE FINDINGS In the po...

Transplantation of bone marrow cells as well as circulating endothelial progenitor cells (EPC) enhances neovascularization after ischemia. The chemokine receptor CXCR4 is essential for migration and homing of hematopoietic stem cells. Therefore, we investigated the role of CXCR4 and its downstream signaling cascade for the angiogenic capacity of cultured human EPC. Ex vivo, differentiated EPC d...