Objectives: Crocin, a constituent of saffron and yellow gardenia, possesses anti-nociceptive effects. In the present study, we investigated the effects of intra-fourth ventricle injection of crocin in a rat model of orofacial pain. The contribution of opioid system was assessed using intra-fourth ventricle injection of naloxone, an opioid receptor antagonist. Materials and Methods: A guide cann...

objectives: crocin, a constituent of saffron and yellow gardenia, possesses anti-nociceptive effects. in the present study, we investigated the effects of intra-fourth ventricle injection of crocin in a rat model of orofacial pain. the contribution of opioid system was assessed using intra-fourth ventricle injection of naloxone, an opioid receptor antagonist. materials and methods: a guide cann...