background: cryptosporidium species are important cause of diarrheal diseases in both developing and developed countries. this study aimed to compare the perfor-mance of several molecular methods for identification of cryptosporidium species, and to detect genetic variation among each of these species isolated from iran, ma-lawi, nigeria, vietnam and the united kingdom. methods: the oocysts dna...

background: the high resolution melting (hrm) method is a new scanning method for detecting unknown changes in dna and its advantages have persuaded researchers to recruit it as a screening method. objectives: here, we developed a hrm method to screen r188h snp (rs3218536) of xrcc2 and compared the results with a well known pcr-rflp technique. materials and methods: genomic dna samples from 350...

objective(s): candidiasis infection caused by candida albicans has been known as a major problem in patients with immune disorders. the objective of this study was to genotype the c. albicans isolates obtained from oral cavity of patients with positive human immunodeficiency virus (hiv+) with or/and without oropharyngeal candidiasis (opc). materials and methods:a total of 100 c. albicans isolat...

background: the present study was aimed to investigate molecular diversity of echino-coccus granulosus isolates collected from human clinical samples using two mitochondrial genes cox1 and nad1 in iran . methods: forty seven human hydatid cysts were collected through surgery from two hospitals in tehran during 2010-2012. to determine the fertility of protoscoleces, the cyst fluids were subjecte...

background: hydatidosis or cystic hydatid disease is one of the most important diseases in human and animals. identification of strains is important for improvement of control and prevention of dis-ease. the aim of this study was to determine the strains isolated from human and domestic animals in ilam province, iran, using pcr-rflp method. methods: respectively, 30 and 4 animal and human hydat...

â  â  background hepatitis c virus (hcv) infection is responsible for considerable morbidity and mortality worldwide. the hcv genotype has a geographic distribution and an important role in clinical and histological outcomes. this study determined hcv genotypes and their related risk factors among patients from khuzestan province, southwest iran. methods in a cross-sectional study, 223 patients...

hepatitis c is a major cause of liver related morbidity and mortality worldwide and represents a major public health problem. depending on genomic organization, the virus is divided into six genotypes and a number of subtypes. different genotypes are seen in different parts of the world. genotype one is difficult to treat, while genotypes 2 and 3 are easy to treat. therefore, identification of ...