Objective - to evaluate both in-vivo and in-vitro antibacterial property of Aloe vera.L fresh gel. Design - experimental study. Animals - five adult male mixed breed dogs aged 2-4 years. Procedures - for in-vivo experiment, under general anesthesia and sterile condition 8 symmetrical full-thickness wounds measured 2 cm×2 cm were surgically created on the back of each dogs o...

Objective- to consider the influence of Aloe vera L fresh gel on healing process histopathologically. Design- Experimental study Animals- Five adult male mixed breed dogs aged 2-4 years Procedures- Eight symmetrical full-thickness wounds were surgically created on the back of all five dogs under general anesthesia and sterile condition. After wound creation, 1 ml fluid containing 10...

background: honey has been shown to accelerate wound healing, which is especially important in the management of patients with full-thickness wounds of skin in dermatologic surgeries.   objective: to evaluate the effects of honey in accelerating healing of full-thickness skin wounds in mice.   methods: two groups of male nmri mice (n=12) were subjected to full-thickness skin wounds under genera...

Background:Honey has been shown to accelerate wound healing, which is especially important in the management of patients with full-thickness wounds of skin in dermatologic surgeries. Objective: To evaluate the effects of honey in accelerating healing of full-thickness skin wounds in mice. Methods: Two groups of male NMRI mice (n=12) were subjected to full-thickness skin wounds under general ane...

Healing of burn wounds is often associated with scar formation due to excessive inflammation and delayed wound closure. To date, no effective treatment is available to prevent the fibrotic process. The Renin Angiotensin System (RAS) was shown to be involved in fibrosis in various organs. Statins (e.g. Atorvastatin), Angiotensin receptor antagonists (e.g. Losartan) and the combination of these d...

Bacterial infections, especially multidrug-resistant bacterial infections, are an increasingly serious problem in the field of wound healing. Herein, bacterial cellulose (BC) decorated by 4,6-diamino-2-pyrimidinethiol (DAPT)-modified gold nanoparticles (Au-DAPT NPs) is presented as a dressing (BC-Au-DAPT nanocomposites) for treating bacterially infected wounds. BC-Au-DAPT nanocomposites have be...

BACKGROUND Full-thickness burn wounds require excision and skin grafting. Multiple surgical procedures are inevitable in managing moderate to severe full-thickness burns. Wound bed preparations prior to surgery are necessary in order to prevent wound infection and promote wound healing. Honey can be used to treat burn wounds. However, not all the honey is the same. This study aims to evaluate t...

OBJECTIVE To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials. DATA SOURCES Cochrane Library, MEDLINE, EMBASE, PubMed, reference lists and databases were used to seek randomised controlled trials. Seven randomised trials involved superficial burns, partial thickness burns, moderate to severe burns that included full thickness...

Objective- This study aimed at evaluation of histopathological findings of application of chitosan- nano selenium biodegradable film on full thickness excisional wound healing in rats. Design- Experimental Study Animals- Seventy-two male Wistar rats Procedures- Animals were randomized into six groups of 12 animals each. Group I: Animals with created wounds and no...

BACKGROUND Within the plastic surgery community, it is widely believed that waiting a minimum of 6 to 12 months after patient cessation of systemic retinoid therapy is necessary before proceeding with elective surgery. OBJECTIVE The authors investigate partial- and full-thickness wound healing after treatment with systemic isotretinoin in a porcine model. METHODS Following institutional app...