it is well-known that deficiency or over exposure to various elements has noticeable effects on human health. the effect of an element is determined by several characteristics, including absorption, metabolism, and degree of interaction with physiological processes. iron is an essential element for almost all living organisms as it participates in a wide variety of metabolic processes, includin...

during the course of our studies on archaeometallurgy in southeastern iran, we tried to survey the triangle of the sirdjān, neiriz and shahr- e- bābak. as a result, remains of old iron mining residues of smelting furnaces, and iron smelting slag heaps were observed and recorded. a few samples of iron ore and smelting slag have been analysed classically and instrumentally. according to the acq...

background: pregnant women take iron supplements in order to prevent iron deficiency anemia which may have undesirable effects for both the mother and fetus. this study aimed to compare the daily and intermittent dose of iron supplementation in blood and iron indices in healthy pregnant women.methods: in this clinical trial study, 145 healthy pregnant women were selected with hbx0511g%. the par...

background: it is clear that helicobacter pylori (h. pylori) is a spiral bacterium that infects human and causes gastritis and peptic ulcer. the aim of this study was to determine the relationship between h .pylori infection and the iron status of the body. methods: this study was conducted in shahid beheshti hospital of babol university of medical sciences, babol, iran from august 2007 to july...

background: it is intriguing and imperative that the comparison of the iron preparations in hemodialysis (hd) patients. th is study aimed to observe the short-term effi cacy of parenteral iron sucrose and ferric chloride in hd patients. materials and methods: this was a consecutive 10-week single-blind study in taiwan. an intravenous iron supplement of 100 mg/week was administered as an infusio...

transfusion-dependent patients such as those suffering from β-thalassaemia develop a fatal secondary haemosiderosis and consequently a selective iron chelator must be used to relieve such iron overload. 3- hydroxypyridin-4-ones are selective for iron(iii) under most biological conditions, but unlike desferrioxamine, are efficiently absorbed when administered orally. in this study, the synthesis...

iron overload is a serious clinical condition which can be largely prevented by the use of iron-specific chelating agents. in this study, the synthesis and determination of partition coefficients (kpart) of a range of n-alkyl hydroxypyridinones, as orally active iron chelators, are described. synthesis of n-aryl hydroxypyridinones was achieved via a single step synthetic pathway. in this method...

background : it has been suggested that inflammatory state due to obesity can lead to alteration in iron metabolism. women in reproductive age are at higher risk of iron deficiency. in this study, we aimed to evaluate inflammatory status and iron markers in young overweight and obese women. subjects and methods: in this study, 120 young and healthy women with a bmi ≥ 25 kg/m2 were enrolled. bio...