نتایج جستجو برای: Knock-down

تعداد نتایج: 222092  

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری 1391

مقدمه شبکه آندوپلاسمی به واسطه وجود چاپرون هایی نظیر grp78 نقش مهمی در بلوغ و تاخوردگی پروتئینها بازی میکند. تجمع پروتئین های تا نخورده در شبکه آندوپلاسمی منجر به فرایند استرس شبکه آندوپلاسمی می شود که پاسخ به این فرایند با کاهش کلی سنتز پروتئین و افزایش بیان چاپرون هایی نظیر grp78 همراه می باشد. در سلولهای رنگدانه دار شبکیه چشم افراد بالغ طولانی شدن فرایند er stress باعث مرگ برنامه ریزی شده ا...

Journal: :iranian journal of public health 0
h. ladonni s. sadaeghiani

trasal-contact method test using glass petri-dish rather than the conventional glass jar was used to evaluate the permethrin toxicity and synergism effect of piperonal butoxode (pbo) on nymphae of five strains of blattella germanica (l.). the test was carried out on 2-3 days old of first nympal stage, at four replicates of 10 cockroaches. the susceptible strain showed t50 and kt50 of 12.81 and ...

Journal: :Nature Reviews Genetics 2001

Journal: :Genome Biology 2002

Objectives:The expression levels of heat shock proteins (HSPs) are elevated in many cancers, and this overexpression is often associated with both a poor survival and a therapeutic outcome. Curcumin is an anti-cancer agent that also induces a heat shock response. HSPs confer resistance to curcumin-induced apoptosis in cancerous cells. The aim of the current study was to analyze variations in th...

Journal: :Riset Arsitektur (RISA) 2018

Journal: :EuPA Open Proteomics 2015

Journal: :iranian journal of basic medical sciences 0
tianyun pang obstetrics and gynecology department of the first affiliated hospital of guangdong medical college, no. 57 avenue of the people, zhanjiang, guangdong province 524023, pr china cancer institute of guangdong medical college, no. 1 xincheng road, dongguan, guangdong province 523808, pr china sen wang cancer institute of guangdong medical college, no. 1 xincheng road, dongguan, guangdong province 523808, pr china min gao cancer institute of guangdong medical college, no. 1 xincheng road, dongguan, guangdong province 523808, pr china people's hospital of dongguan, no. 3 south of wandao road, dongguan, guangdong province 523059, pr china haixian kang cancer institute of guangdong medical college, no. 1 xincheng road, dongguan, guangdong province 523808, pr china

objective(s):eukaryotic translation initiation factor 4e (eif4e) is overexpressed in cervical cancer (cc). however, the molecular mechanisms are unclear. this study aimed to investigate the molecular mechanism of eif4e gene overexpression in cc. materials andmethods:the human papillomavirus (hpv) type 18 e7 and eif4e mrnas were measured following knock down or overexpression of e7 gene by rt-pc...

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