Mechanical interaction of cells and their surroundings are prominent in mechanically active tissues such as cartilage. Chondrocytes regulate their growth, matrix synthesis, metabolism, and differentiation in response to mechanical loadings. Cells sense and respond to applied physical forces through mechanosensors such as integrin receptors. Herein, we examine the role of mechanical stimulation ...

Magnetic nanoparticles (MNPs) functionalized with targeting moieties can recognize specific cell components and induce mechanical actuation under magnetic field. Their size is adequate for reaching tumors and targeting cancer cells. However, due to the nanometric size, the force generated by MNPs is smaller than the force required for largely disrupting key components of cells. Here, we show th...

background: magnetic nanoparticles in a variable magnetic field are able to produce heat. this heat (42-45°c) has more selective effect on fast dividing cancer cells than normal tissues. methods: in this work magnetite nanoparticles have been prepared via co-precipitation and phase identification was performed by powder x-ray diffraction (xrd). magnetic parameters of the prepared nanoparticles ...

This paper scrutinizes the magnetic field effect to deliver the superparamagnetic nanoparticles (SPMNs) through the Blood Brain Barrier (BBB). Herein we study the interaction between the nanoparticle (NP) and BBB membrane using Molecular Dynamic (MD) techniques. The MD model is used to enhance our understanding of the dynamic behavior of SPMNs crossing the endothelial cells in the presence of a...

in this research, some more applicable ferrofluids are produced and their mechanical specifications are measured, experimentally. also, their treatments in the ventilated cavity geometry are assessed numerically. the magnetite nanoparticles are produced by a chemical combination of fe2+ and fe3+ with nh3. in order to solve the nanoparticles in the new mediums, a proper coating is added to them....

We report selective and directional actuation of elastomer films utilizing magnetic anisotropy introduced by chains of Fe3O4 magnetic nanoparticles (MNPs). Under uniform magnetic fields or field gradients, dipolar interactions between the MNPs favor magnetization along the chain direction and cause selective lifting. This mechanism is described using a simple model.

Ferrofluids are stable colloidal suspensions of nanosize ferromagnetic particles in either an aqueous or an oil-based solvent1. In the presence of a magnetic field gradient within a ferrofluid, magnetic forces and torque are developed to drive magnetic particles, which subsequently draw along the liquid solvent carrier. This allows continuous actuation and precise positioning of the ferrofluid ...