Background: Melasma is a pattern of facial pigmentation that affects upper lip, cheeks, forehead and chin. The disease is seen mainly in 30-55 year old women, and may be regarded as a physiological change in pregnancy. Its etiologic nature is still unknown. Objective: To determine the prevalence of melasma in women in Ardebil city. Patients and Methods: The study was cross sectional-descr...

Estrogens are widely used in hormone replacement therapy, gynecology, urogynecology and rarely in dermatology. Non-therapeutic use of estrogens is very widespread. Estrogens are used as contraceptives, which cause a lot of serious side effects. A common clinical problem is skin hyperpigmentation (melasma), occurring mainly in women who take contraceptives with high doses of estrogens. But low d...

Objectives: This study was to evaluate the clinical profile and dermatoscopic classifications of melasma. Methods: A detail assessment, examinations were performed all patients. Clinical photographs taken with full precautions minimize expression identity patient. Dermatoscopic evaluation each subject done. USB Digital Magna-scope 8LED light source, 20x 200x magnification 2Mega Pixel image sens...

Melasma is an acquired increased pigmentation of the skin, characterized by gray-brown symmetrical patches, mostly in the sun-exposed areas of the skin. The pathogenesis is unknown, but genetic or hormonal influences with UV radiation are important. Our present research aims to study the clinicoepidemiological pattern and the precipitating or provocation factors in melasma. A total of 36 patien...

BACKGROUND Treatment of melasma is unsatisfactory most of the times. Hormonal role is shown to exist in pathogenesis of the melasma, and sex-hormone related drugs may have an effect on melasma. AIM To investigate efficacy of 1% flutamide cream versus 4% hydroquinone cream on melasma. METHODS In a parallel randomized clinical trial, 74 women with melasma were allocated to receive a sunscreen...

BACKGROUND Melasma is a facial dyspigmentation which is a common complaint in patients with darker skin tones. Many current therapies used for this condition are ineffective and can cause significant adverse effects. OBJECTIVE The purpose of this study was to evaluate the role of erbium:YAG laser resurfacing in the management of refractory melasma. METHODS Ten female patients with melasma u...

BACKGROUND Melasma is a chronic, acquired hyperpigmentation disease on sun-exposed areas of the skin, which affects patients' quality of life. OBJECTIVE To assess the impact on the quality of life of women living in Florianópolis, Brazil, through questionnaire (MelasQol), and investigate the clinical aspects and risk factors for melasma, correlating them with the MelasQol scores. METHODS Th...

BACKGROUND Melasma is a common skin pigment disorder with a difficult clinical response to treatment. OBJECTIVES To evaluate the clinical efficacy and safety of the association of Belides, Emblica and Licorice 7%, compared to Hydroquinone 2%, in the treatment of melasma. METHODS After 60 days of exclusive use of an SPF35 sunscreen, 56 women, 18 to 60 years of age, phototypes I to IV, with e...

BACKGROUND Melasma is a common chronic and relapsing acquired dyschromia. Skin microneedling was reported resulting sustained long-term improvement of recalcitrant melasma, however, the exact mechanism that promotes this skin lightening is not known. This study aimed to investigate clinical and histologic alterations promoted by skin microneedling in facial melasma. METHODS Open pilot trial i...

Background and purpose: Melasma is a common skin pigmentation disorder that manifests as hyperpigmented macules and patches. Genetic predisposition, sun exposure, and pregnancy are known risk factors for melasma. Previous studies have suggested that thyroid disorders may be associated with melasma. Given the fact that vitamin D affects and stimulates the production of melanin by melanocytes, th...