Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability...

background: so far, non-invasive diagnostic approaches such as ultrasound, magnetic resonance imaging, or blood tests do not have sufficient diagnostic power for endometriosis disease. lack of a non-invasive diagnostic test contributes to the long delay between onset of symptoms and diagnosis of endometriosis. objective: the present study focuses on the identification of predictive biomarkers i...

metabolomics studies provide useful information about health and disease status. metabolite based investigations on various cancers is a powerful approach to diagnosis, prognosis and therapy of cancer diseases. recently by using advanced analytical techniques such as nmr and ms and its hyphenation methods, global metabolic profiling of diseases has been possible. it is predictable that internat...

Background: Chronic kidney disease (CKD), characterized by progressive loss of renal function, is becoming a growing problem in the general population. New analytical technologies such as “omics”-based approaches, including metabolomics, provide a useful platform for biomarker discovery and improvement of CKD management. In metabolomics studies, not only prediction accuracy is ...

metabolome analysis is used to evaluate the characteristics and interactions of low molecular weight metabolites under a specific set of conditions. in cirrhosis, hepatocellular carcinoma, non-alcoholic fatty liver disease (nafld) and non-alcoholic steatotic hepatitis (nash) the  liver  does not function thoroughly due to long-term damage. unfortunately the early detection of cirrhosis, hcc, na...

With ever-increasing amounts of metabolomics data produced each year, there is an even greater need to disseminate data and knowledge produced in a standard and reproducible way. To assist with this a general purpose, open source metabolomics repository, MetaboLights, was launched in 2012. To promote a community standard, initially culminated as metabolomics standards initiative (MSI), COordina...

Over the past decade, metabolomics has emerged as an important technique for systems biology. Measuring all the metabolites in a biological system provides an invaluable source of information to explore various cellular processes, and to investigate the impact of environmental factors and genetic modifications. Nuclear magnetic resonance (NMR) spectroscopy is an important method routinely emplo...

Metabolomics is an extension of the omics concept and experimental approaches. However, is metabolomics just another trendy omics fashion perturbation or is metabolomics actually delivering novel content and value? This article highlights some recent advances that definitely support the role of plant metabolomics in the movement toward greener pastures.