Background: Type 1 diabetes (T1D) is one of the most common chronic diseases in children, and nephropathy is a serious microvascular complication of T1D, which is associated with high mortality and morbidity. This study aimed to investigate the prevalence of diabetic nephropathy and comorbidities in children with T1D. Methods: This cross-sectional study was conducted on 208 children (aged 1–18...

Aims: Diabetic nephropathy is one of the consequences of type 1 and type 2 diabetes and one of the main causes of End-Stage Renal Disease (ESRD) as well as an important risk factor for cardiovascular morbidity and death. The aim of this study was to identify the risk factors for diabetic nephropathy in diabetic patients. Instruments & Methods: In this cross-sectional descriptive study, 121 pat...

conclusions in conclusion, the ace and pparg genes do not have a key role in conferring risk for diabetic nephropathy. results ace id genotypes followed hardy-weinberg equilibrium in both cases and controls. but p12a genotypes deviated from hardy-weinberg equilibrium in diabetic controls. chi2 test was applied for the analysis of genotypic distributions in genotypic and dominant models. odds ra...

Nephropathy is a common diabetes complication. ERRFI1 gene which participates in various cellular pathways has been proposed as a candidate gene in diabetic nephropathy. This study aimed to investigate the role of +808T/G polymorphism (rs377349) in ERRFI1 gene in diabetic nephropathy. In this case-control study, patients including diabetes with nephropathy (DN=104), type 2 diabetes without neph...

conclusions in issns, bone strength recovered one month after terminating stx. in igan, bone strength recovered 10 months after tapering of stx. results in issns, the bmd and s-alp levels were significantly lower in phase 1 than in phase 0; however, scores and levels returned to baseline in phase 2. in igan, bmd was significantly lower in phase 2 than in phase 0 while s-alp levels were signific...

background: contrast induced nephropathy (cin) is one of the most common complications after radiographic procedures using intravascular radiocontrast media. the aim of the current study was to assess the effect of atorvastatin on prevention of cin in patients undergoing coronary angiography. materials and methods: in a clinical trial study, 200 patients referred for angiography were randomly d...