Oral lichen planus is a chronic inflammatory immune-mediated disease. ICAM-1 and VCAM-1 are vascular adhesion molecules that their receptors are located on endothelial cells and leukocytes. The aim of this study is the immunohistochemical evaluation of VCAM1 and ICAM1 in oral lichen planus and to compare these two markers with normal mucosa for evaluation of angiogenesis. This descriptive-analy...

Background and aim: Lichen planus (LP) is a chronic inflammatory disease with an uncertain pathogenicity. Recent reports have revealed that angiogenesis is effective in the pathogenesis and biologic behavior of lesions. Considering the limitations of the studies related to angiogenesis in oral LP (OLP) and the controversial results, the present study aimed to compare the expression of vascular ...

oral lichen planus is a chronic inflammatory immune-mediated disease. icam-1 and vcam-1 are vascular adhesion molecules that their receptors are located on endothelial cells and leukocytes. the aim of this study is the immunohistochemical evaluation of vcam1 and icam1 in oral lichen planus and to compare these two markers with normal mucosa for evaluation of angiogenesis. this descriptive-analy...

oral lichen planus (olp) is a chronic inflammatory disease of the oral mucosa which is considered by the world health organization (who) as a premalignant condition. one step in malignant development is so called epithelial mesenchymal transition (emt), a process whereby epithelial cells acquire mesenchymal characteristics. a factor known to induce emt is the transforming growth factor-β (tgf-β...

objective: oral mucosal epithelia of smokers and waterpipe users are more susceptible to malignant alterations. the aim of this study was morphometric evaluation of the effects of using waterpipe on normal oral mucosa. materials and methods: in a cross sectional study, cytologic smear samples from the following three different areas: buccal mucosa, lateral surface of the tongue, and floor of th...

Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa which is considered by the World Health Organization (WHO) as a premalignant condition. One step in malignant development is so called epithelial mesenchymal transition (EMT), a process whereby epithelial cells acquire mesenchymal characteristics. A factor known to induce EMT is the transforming growth factor-β (TGF-β...