the article of marc jamoulle shows the importance of the contribution of general practitioners (gps) in improving the quality and the efficiency of the health systems. starting from the concept of quaternary prevention for reducing excessive costs in the preventive procedures, he suggests a change of paradigm in every daily activity of the gp in order to have a stronger ethical approach to the ...

Henry et al. (2007) present a cogent analysis of the use of propranolol in preventing post-traumatic stress disorder (PTSD). They express a wide range of unanswered questions regarding this use of propranolol and criticize the report of the President’s Council on Bioethics (2003) on pharmacologic memory suppression on grounds of its obviously conservative agenda. The authors’ greatest concern i...

This PLoS Medicine Debate examines the different approaches that can be taken to tackle neglected tropical diseases (NTDs). Some commentators, like Jerry Spiegel and colleagues from the University of British Columbia, feel there has been too much focus on the biomedical mechanisms and drug development for NTDs, at the expense of attention to the social determinants of disease. Burton Singer arg...

Abstract We conducted a genealogical analysis of quaternary prevention, an instrument primary health care to address overmedicalization and iatrogenesis, based on related statements interviews with the creators this concept. This tool has been used in reformulation doctor-patient relationship, but limited risk-benefit assessment by using current scientific evidence. In study, we analyze paradox...

The article of Marc Jamoulle shows the importance of the contribution of general practitioners (GPs) in improving the quality and the efficiency of the health systems. Starting from the concept of quaternary prevention for reducing excessive costs in the preventive procedures, he suggests a change of paradigm in every daily activity of the GP in order to have a stronger ethical approach to the ...

The emerging concept of systems medicine (or 'P4 medicine'-predictive, preventive, personalized and participatory) is at the vanguard of the post-genomic movement towards 'precision medicine'. It is the medical application of systems biology, the biological study of wholes. Of particular interest, P4 systems medicine is currently promised as a revolutionary new biomedical approach that is holis...