background: gts, ptsm and atsm are bis-thiosemicarbazone ligands used in the preparation of copper radiopharmaceuticals. chemical structure of these materials indicates that they should have radio-protective effects. objective: to study the radio-protective effects of gts, ptsm and atsm. methods: this study has focused on radio-protective effects of these compounds at different doses (20, 40 an...

Ionizing radiation interacts with biological systems to produce reactive oxygen species and reactive nitrogen species which attack various cellular components. Radio-protectors act as prophylactic agents to shield healthy cells and tissues from the harmful effects of radiation. Past research on synthetic radio-protectors has brought little success, primarily due to the various toxicity-related ...

Background: GTS, PTSM and ATSM are bis-thiosemicarbazone ligands used in the preparation of copper radiopharmaceuticals. Chemical structure of these materials indicates that they should have radio-protective effects.Objective: To study the radio-protective effects of GTS, PTSM and ATSM. Methods: This study has focused on radio-protective effects of these compounds at different doses (20, 40 and...

background: synthetic radio-protective agents like aminothiols are toxic and fda approved agent amifostine is no exception. some ayurvedic herbs have shown radioprotective potential. this study was carried out to test and compare the radioprotective potential of curcuma longa (cl) tinospora cordifolia (tc), zizyphus mauritiana (zm) and ocimum sanctum (os) against 2gy gamma irradiation in swiss ...

conclusions this case report supports the beneficial role of erythropoietin in function, maintenance, and recovery of neurons. erythropoietin is a double-edge sword, as long-term erythropoietin therapy has some complications, like thromboembolism and stroke. recent studies suggested that erythropoietin should be given as single high dose to exert a rapid neuro-protective effect with minimal hem...

occupational exposure to cytotoxic drugs is a global concern. we conducted this cross-sectional study in 2012 to describe the adverse effects experienced by nurses working in one of chemotherapy facilities affiliated to shiraz university of medical sciences, shiraz, southern iran, and their proper use of personal protective equipment and educational programs. the frequency of side effects repor...

Background: Synthetic radio-protective agents like aminothiols are toxic and FDA approved agent amifostine is no exception. Some Ayurvedic herbs have shown radioprotective potential. This study was carried out to test and compare the radioprotective potential of Curcuma longa (CL) Tinospora cordifolia (TC), Zizyphus mauritiana (ZM) and Ocimum sanctum (OS) against 2Gy gamma irradiation ...

PURPOSE These comments suggest a division of radiation protective agents on the grounds of their mechanism of action that increase the radio resistance of an organism. CONCLUSION Given below is the division of radiation protective agents on the basis of their mechanism of action into 3 groups: 1) Radiation protective agents, with the implementation of radiation protective action taking place ...

An attempt made to construct a model of relationship of the radioprotective and carcinogenic properties of biologically active compounds with their electron and information factors. We discovered a simple quantitative structure – activity relationships between the radioprotective effectiveness of chemicals and their molecular structure. It is established that carcinogenic properties of chemical...