نتایج جستجو برای: Renal damage
تعداد نتایج: 458318 فیلتر نتایج به سال:
clinical data showed consumption of buckwheat played a very positive role in the relief of diabetes and its complications. the purpose of this study was to explore the effects and mechanisms of the overall flavonoids from buckwheat flowers and leaves (tfbfl) on renal damage in type 2 diabetes mellitus (t2dm) rats. seventy male wistar rats were selected. ten rats were randomly allocated into a n...
vesicoureteral reflux (vur) is one of the most important causes of urinary tract infection and renal failure in children. it is a potentially self-limited disease. the aim of this study was to evaluate the clinical course and significant factors in children with primary vur. the medical charts of 125 infants and children (27.2 % males, 72.8% females) with all grades of primary vur were retrospe...
Background: In a recent study, we were able to demonstrate a role for leukocyte transfer in the induction of liver damage in recipient mice after induction of IR (60 min of bilateral renal artery occlusion and 3 hrs reperfusion) injury in donors. The present study investigates the role of leukocyte transfer in the induction of kidney damage in recipient mice after induction of renal IR injury i...
Introduction: Liver ischemia/reperfusion (IR) is a major clinical problem, which occurs during several conditions such as liver damage, trauma and transplantation. Recent studies indicate that IR-induced acute liver failure causes injuries of distant organs such as heart and lungs by systematic inflammatory responses. Therefore, in the present study, effects of hepatic IR induction were stud...
Background& objectives: Renal ischemia-reperfusion (IR) damage occurs during renal transplantation in end-stage renal disease (ESRD) patients which activate immune responses. Inflammatory responses by increased levels of cytokines can lead to acute kidney injury (AKI) that contributes to the loss of renal grafts and graft dysfunction. The purpose of this study was to review the therapeutic effe...
Background: Previous studies have shown increases in endothelin (ET) concentration of plasma and renal tissues in acute renal failure (ARF). ET has a potent vasoconstrictor effect, through binding with its ETA receptors, and may play some roles in renal hemodynamic dysfunction in ARF.Objective: To examine the beneficial effect of a selective ETA-receptor antagonist on renal dysfunction and tis...
Background and purpose: Diabetes is a health problem worldwide with increasing prevalence in most countries. Nephropathy is a common microvascular complication of diabetes. Diabetes is directly associated with oxidative stress and mitochondrial damage that result in renal tissue damage. This study evaluated the efficiency of nanoceria in attenuation of oxidative damage in renal isolated mitocho...
this study investigated the effect of berberine on the hepatic dysfunction and histological damage induced by renal ischaemia/ reperfusion (i/r) at an early stage. there were four groups (n=7). in ber+i/r group, rats received berberine (ber; 15 mg/kg/day) orally for 7 days before induction of ischemia. i/r group received distilled water orally for 7 days. in sham and ber+sham groups in which ar...
Acute Pyelonephritis (APN) is one of the most common bacterial infections seen in children that may lead to renal scarring. Vesicoureteral reflux (VUR) is an important risk factor of renal damage but not the only one. Materials and Methods: In order to determine the association between dimercaptosuccinic acid (DMSA) scintigraphic and voiding cystourethrographic findings, a retrospective study w...
Introduction: Acute kidney injury (AKI) has been known as a complex clinical complication in diabetic patients. The main cause of AKI is ischemia/reperfusion injury (IRI). This study was designed to investigate the protective effects of GABA on renal IRI in hyperglycemic female and male rats. Methods: Sixty STZ induced diabetic male and female Wistar rats were categorized in 10 groups (5 fem...
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