For production of protease by a new strain, Serratia marcescens SB08, optimization of the fermentation medium and environmental conditions, were carried out by applying factorial design and response surface methodology. The results of factorial design showed that pH, agitation, incubation time and yeast extract were the key factors affecting protease production. The optimal cultural conditions ...

this paper describes optimization method that combines the plackett-burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of l-asparaginase by serratia marcescens sb08. four medium factors, from out of 11 medium factors, were screened by plackett-burman design experiments and subsequent optimization process to find out the o...

This paper describes optimization method that combines the Plackett-Burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of L-asparaginase by Serratia marcescens SB08. Four medium factors, from out of 11 medium factors, were screened by Plackett-Burman design experiments and subsequent optimization process to find out the o...

serratia marcescens (s.m) is a species of gram–negative bacteria in the family enterobacteriaceae. a human pathogen, s. marcescens is involved in nosocomial infections, particularly in urinary tract and wound infections. this report describes a 63 years-old man that referred to hospital with dyspnea fc iv and he underwent cardiac valves replacement surgery with a diagnosis of severe mitral sten...

  Serratia marcescens (S.M) is a species of gram–negative bacteria in the family enterobacteriaceae. A human pathogen, S. marcescens is involved in nosocomial infections, particularly in urinary tract and wound infections. This report describes a 63 years-old man that referred to hospital with dyspnea FC IV and he underwent cardiac valves replacement surgery with a diagnosis...

As an investigative study, the potent bacterium Serratia marcescens SB08 was screened from enteric gut of sulfur butterfly (Kricogonia lyside). Its pigment potential tested, and identified as prodigiosin by structural studies using High Performance Liquid Chromatography (HPLC), Gas Chromatography–Mass Spectroscopy (GC–MS), Fourier Transform Infrared (FTIR) Nuclear Magnetic Resonance (NMR). Vari...

Serratia marcescens is a member of the family Enterobacteriaceae. It has emerged in recent years as an opportunistic pathogen of nosocomial infections. Some biotypes of Serratia marcescens produce the non-diffusible red pigment prodigiosin. Though both pigmented and non-pigmented biotypes may be pathogenic for humans, the non-pigmented biotypes are more virulent due to cytotoxin production and ...

BACKGROUND The aim of our study was to investigate and control an outbreak and identify risk factors for colonization and infection with Serratia marcescens in two departments in Tartu University Hospital. METHODS The retrospective case-control study was conducted from July 2005 to December 2006. Molecular typing by pulsed field gel electrophoresis was used to confirm the relatedness of Serra...

Endogenous bacterial endophthalmitis in infants is uncommon. We recently examined and treated an infant who presented with pink hypopyon which followed a Serratia marcescens septicaemia. Culture of the aspirate from the anterior chamber showed no red blood cells, and grew Serratia marcescens, which was also isolated from the tip of the child's umbilical artery catheter. The presence of a pink h...