this is a picture presentation of myeloproliferative disorder developing to longitudinal melanonychia as a side effect of hydroxyurea. keywords: melanonychia, hydroxyurea, side effect.

objective concern for side-effects of therapy related to treatment of childhood malignancies is becoming an increasingly important topic. in this study, we evaluated extent of vincristine (vcr) induced neurotoxicity in a group of children who underwent chemotherapy, with vcr being part of the regimen. materials & methods in this investigation, for 75 children (54% boys, 46% girls), aged between...

labor pain is one of the most tiresome types of pain. so human has been seeking to allay this pain until now. administration of a suitable agent such as entonox during labor is very beneficial for childbirth outcomes. entonox can be administered in two ways: intermittently and continuously. the aim of this study is to demonstrate whether continuous method is as safe as intermittent method? this...

background: methotrexate has an important role in treatment of acute leukemia. we measured methotrexate level in csf and blood of children with acute lymphoblastic leukemia to determine complications and outcomes. materials and methods: one hundred and twenty patients (73 male, 47 female), with mean age at diagnosis of 6.1 years (11mo_15years) entered the study. patients were divided into two g...

oral contraceptive pills have several side effects especially on the gastrointestinal tract and liver. absorption of low dose (ld) pills by the vaginal route avoids the first pass of the steroids through these tracts and probably has fewer side effects. this study was a cohort study for evaluation of side effects and acceptability of ld pills administered by the vaginal route. in a clinical tri...

how to cite this article: talebian a, goudarzi rm, mohammadzadeh m , mirzadeh as. vincristine-induced cranial neuropathy. iran j child neurol. 2014 winter; 8(1):66-68.   abstract vincristine (vcr) is a vinca alkaloid that is used for treatment of many malignancies. the vinca alkaloids are neurotoxic, usually causing a peripheral neuropathy, but cranial neuropathies are rare as side effects.  de...

remifentanil is an ultra short acting opioid that is suitable for many operations and is wildly used for induction and maintenance of anesthesia. in this article we have reported the incidence of abdominal pain after cataract surgery in patients with remifentanil based anesthesia. this study is a randomized single blind clinical trial on 300 patients who were candidates for elective cataract su...

this cross sectional study was carried out between 1993 to 1998 at razi skin hospital, the affiliated dermatology department of tehran university of medical sciences. eight hundred patients receiving etretinate for various skin diseases took part in this study. among them, 457 patients with first admission to dermatologic clinic who had at least four regular sequential visits and responding to ...

ôbjective: to compare the effectiveness and safety of the methylphenidate produced in ïran (stimdate®) with its original brand (ritalin®) in children with âttention deficit hyperactivity disorder (âdhd). methods: ïn this double-blinded randomized clinical trial, 30 patients with âdhd who were 6 to 16 years old, were divided into two groups: 15 in stimdate® and 15 in ritalin® group. the two grou...