The cause of infertility is unexplained in about 22-28% of all infertile couples. The prognosis for spontaneous pregnancy in such couples is better than in those with diagnosed causes of infertility. Traditional treatment options in this group have included expectant management, clomifene citrate, intrauterine insemination with (super ovulation plus intrauterine insemination) or without (intrau...

The chromatographic separation of gonadotropin-inhibiting substance in the extract obtained from adult male urine according to the method of Johnsen was attempted on a Sephadex G-100 column. The ovulation assay was employed to detect the inhibitor in the fractions using female mice, 19-20 days old, which received PMS and HCG to obtain a minimum constant ovulation. In the chromatography of the e...

Background: The objectives of a series of studies undertaken was to improve farm animal reproductive efficiency in terms of embryo production efficiency, conception rate and litter size by immunoneutralization of inhibin in conjunction with other conventional reproductive techniques. Materials and Methods: A recombinant porcine inhibin alpha-subunit mature peptide was produced by mass scale and...

Endothelin-2 (EDN2), a potent vasoconstrictive peptide, is transiently produced by periovulatory follicles at the time of ovulation when corpus luteum (CL) formation begins. EDN2 induces contraction of ovarian smooth muscles ex vivo via an endothelin receptor A-mediated pathway. In this study, we aimed to determine if EDN2 is required for normal ovulation and subsequent CL formation in?vivo. In...

background: the effect of smoking cigarettes is followed by diverse effects on ovaries and developing follicles but the effect of passive smoking on ovarian function is unknown. on the other hand, the ovarian response to induction is a very important step in assisted reproduction. the aim of this study is to compare ovarian response in passive smokers and non-passive smokers in an assisted repr...

Background The effect of smoking cigarettes is followed by diverse effects on ovaries and developing follicles but the effect of passive smoking on ovarian function is unknown. On the other hand, the ovarian response to induction is a very important step in assisted reproduction. The aim of this study is to compare ovarian response in passive smokers and non-passive smokers in an assisted repro...

This review examines the one humped camel (Camelus dromedarius) a considerable number of the dromedary about 50,000 is found in the semi-arid part of Northern Nigeria. Apart from the wide use of the camel as a draught animal the camel now serve as a source of milk, meat and hide in this region, these notes examines the anatomical basis of reproduction, pregnancy, and its diagnosis, fertility, a...

Background: The effect of smoking cigarettes is followed by diverse effects on ovaries and developing follicles but the effect of passive smoking on ovarian function is unknown. On the other hand, the ovarian response to induction is a very important step in assisted reproduction. The aim of this study is to compare ovarian response in passive smokers and non-passive smokers in an assisted repr...

background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cau...