background: suppressive therapy with levothyroxine for reducing the size of thyroid nodules has not been really accepted. the purpose of this study was to assess the effect of levothyroxine on the size of benign thyroid nodules. methods: forty patients with confirmed benign nodule were randomly divided into two groups. group i received 50?g/day levothyroxin for six months but group ii did not t...

recurrent vulvovaginal candidiasis (rvvc) is seen in 5% of women with candida vaginitis. use of fluconazole as prophylactic treatment has been suggested for rvvc. the aim of the present study was to evaluate the efficacy of fluconazole suppressive therapy in rvvc patients, as a randomized, placebo-controlled, double-blind prophylactic study. among the 330 women with acute symptomatic vulvovagin...

Introduction:  In order to assess echocardiographic left ventricular functional indices in patients with differentiated thyroid carcinoma (DTC), after L-T4 withdrawal (short-term overt hypothyroidism) and during TSH suppressive therapy, we have evaluated cardiac hemodynamics in a single cohort study. Methods: 24 patients with DTC were studied in two phases: 1: at least 4 weeks after L-T4 withd...

introduction:  in order to assess echocardiographic left ventricular functional indices in patients with differentiated thyroid carcinoma (dtc), after l-t4 withdrawal (short-term overt hypothyroidism) and during tsh suppressive therapy, we have evaluated cardiac hemodynamics in a single cohort study. methods: 24 patients with dtc were studied in two phases: 1: at least 4 weeks after l-t4 withdr...

Although combination therapy for HIV infection represents a triumph for modern medicine, chronic suppressive therapy is required to contain persistent infection in reservoirs such as latently infected CD4+ lymphocytes and cells of the macrophage-monocyte lineage. Despite its success, chronic suppressive therapy is limited by its cost, the requirement of lifelong adherence, and the unknown effec...

OBJECTIVES To describe elderly patients treated with prolonged suppressive antibiotic therapy for a prosthetic joint infection (PJI) in cases where the infected prosthesis could not be removed. METHODS All patients aged ≥80 years with a documented PJI and treated with prolonged suppressive antibiotic therapy for more than 6 months were included retrospectively in this study. The following eve...