نتایج جستجو برای Thioacetamide

تعداد نتایج: 435  

Journal: :The Journal of Biophysical and Biochemical Cytology 1959
R. G. Kleinfeld, E. von Haam,

The effect of thioacetamide on dividing cells of regenerating rat liver has been studied. Rats were given daily subcutaneous injections of thioacetamide as a 1 per cent solution at a dosage of 5 mg./100 gm. body weight for 7 to 10 days, subjected to partial hepatectomy, and sacrificed 28 to 31 hours later. Thioacetamide treatment results in striking increases in the nuclear ribonucleoproteins o...

2003
E. VON HAAM,

The effect of thioacetamide on dividing cells of regenerating rat liver has been studied. Rats were given daily subcutaneous injections of thioacetamide as a 1 per cent solution at a dosage of 5 rag./100 gm. body weight for 7 to I0 days, subjected to partial hepatectomy, and sacrificed 28 to 31 hours later. Thioacetamide treatment results in striking increases in the nuclear ribonucleoproteins ...

Journal: :Histology and histopathology 1991
E Muñoz Torres, J I Paz Bouza, A López Bravo, M M Abad Hernández, E Carrascal Marino,

Hepatic cirrhosis is a complex disease in which several biological, biochemical and chemical alterations are combined, none of these alone being sufficient for diagnosis. The morphological characteristics of the final stages of cirrhosis are well known, but the initial lesions and intermediate stages still have not been fully clarified. An experimental model of hepatic cirrhosis by chronic admi...

Journal: :Indian journal of physiology and pharmacology 2003
S M Latha, Mirabel R M S Pai, Pushpalatha K Pai,

groups. Group 1 (n = 10) continued to be on food and water ad libitum and served as control. Group 2 (n = 10) received TA (0.3 g/L) of drinking water (5, 6) and food ad libitum for 16 weeks. Group 3 (n = 10) rats received TA (0.3 g/L) and sodium selenite (4 mg/L) of drinking water (7) and food ad libitum for 16 weeks. Group 4 (n = 10) received TA (0.3 g/L) of drinking water for the first 8 week...

Journal: :Comparative Hepatology 2004
Hiroaki Okuyama, Yasuyuki Shimahara, Hajime Nakamura, Shinichi Araya, Norifumi Kawada, Yoshio Yamaoka, Junji Yodoi,

Introduction Thioredoxin (Trx) is an endogenous multifunctional protein with a redox-active disulfide/dithiol within the conserved active site sequence: -Cys-Gly-Pro-Cys[1]. Trx is also a stress-inducible protein whose expression is enhanced by various types of stresses, e.g., viral infection, exposure to UV light, x-ray irradiation, and hydrogen peroxide (H2O2) [2]. Furthermore, Trx is a scave...

Journal: :Environmental Health Perspectives 1996
R S Mangipudy, P S Rao, H M Mehendale,

In an earlier study we established that timely and adequate tissue repair response following the administration of a six-fold dose-range of thioacetamide (TA; 50, 150, and 300 mg/kg) prevented progression of injury and led to recovery and animal survival. Delayed and attenuated repair response after the 600 mg/kg TA dose resulted in a marked progression of injury and 100% lethality. The objecti...

2007
G. KLEINFELD, EMMERICH VON HAAM,

Partial hepatectomy initiates a complex pattern of cellular changes in the parenchymal cells of the residual liver. The sudden shift of the cell population from normal functional biosyntheses toward syntheses in preparation for cell division provides an ideal system for the study of various aspects of cell metabolism. The morphological and biochemical changes associated with liver restoration h...

2011
Qudsia Begum, Shafaq Noori, Tabassum Mahboob,

Thioacetamide is an organosulfur compound and reasonably anticipated to be a human carcinogenic and toxic effect. Sodium selenite is considered to be an anticarcinogenic and antioxidant, therefore, the aim of study is to evaluate the toxic effect of thioacetamide and the role of sodium selenite on renal tissues by using rat model. 24 Albino wistar rats of male sex (b.w: 200±30gm) were divided i...

Journal: :Molecules 2012
Salim Said Alkiyumi, Mahmood Ameen Abdullah, Ahmed Salim Alrashdi, Suzy Munir Salama, Siddig Ibrahim Abdelwahab, A Hamid A Hadi,

In the Indian system of traditional medicine (Ayurveda) it is recommended to consume Ipomoea aquatica to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of I. aquatica against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD)...

Journal: :Life sciences 2012
Toru Kono, Toshiyuki Asama, Naoyuki Chisato, Yoshiaki Ebisawa, Taishi Okayama, Kouji Imai, Hidenori Karasaki, Hiroyuki Furukawa, Masashi Yoneda,

AIMS Cirrhotic patients commonly have a liver zinc deficiency, which may aggravate liver fibrosis due to the lack of antioxidative effects of zinc. This study examined the ability of polaprezinc, N-(3-aminopropionyl)-l-histidinato zinc, to prevent fibrosis in a rat model of thioacetamide (TAA)-induced hepatic fibrosis. MAIN METHODS Liver cirrhosis was induced by orally administering TAA for 2...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید