نتایج جستجو برای: Toxoplasma gondii
تعداد نتایج: 10498 فیلتر نتایج به سال:
Background and purpose: Toxoplasmosis is an infection caused by an intercellular protozoan called Toxoplasma gondii. Toxoplasma has global expansion and its prevalence is different in regions according to geographical conditions, habits and history of contact with cats. The present study determined the seroepidemiology of toxoplasma in pregnant women attending health centers in two cities i...
Background and purpose: Toxoplasma gondii is a protozoon with worldwide distribution. In spite of increasing information about its biology, treatment of toxoplasmosis is restricted to a few drugs and unfortunately using of each of drugs is associated with significant side effects in patients. It seems that investigation on alternative drugs is necessary. Materials and methods: In case group, c...
The precise diagnosis of the acute toxoplasmosis in pregnant women and immunocompromsied patients has critical importance. Most of the commercially available assays use the whole Toxoplasma soluble extract as the antigen. However, the assays currently available for the detection of specific anti-Toxoplasma antibodies may vary in their abilities to detect serum immunoglobulins, due to the lack o...
The inner membrane complex (IMC) of Toxoplasma gondii as a peripheral membrane system has unique and critical roles in parasite replication, motility and invasion. Disruption of IMC sub-compartment protein produces a severe defect in T. gondii endodyogeny, the form of internal cell budding. In this study, we generated T. gondii virus-like particle particles (VLPs) containing proteins derived fr...
Differentiation between the specific immunoglobulin G (IgG) response to Toxoplasma gondii by a mother and her newborn child is helpful in the diagnosis of congenital infection with T. gondii in newborns without T. gondii-specific IgM and/or IgA antibodies at birth. Previous methods include immunoblotting and complexing T. gondii antigen with the sera from the mother and child and comparing the ...
Toxoplasmosis is an important zoonotic diseases in human and animals. The disease caused by the protozoan Toxoplasma gondii. To determine the infection rate of toxoplasmosis in sheep and goats in east Azarbaijan province of Iran a total of 186 sera, 13 fetal brains, 13 cotyledons and 34 whole blood samples were collected from sheep and goats in Tabriz abattoir during the year 2010. Serum sample...
Background and purpose: Toxoplasma gondii is one of the most common parasitic infections in humans and other vertebrates worldwide. This study aimed at determining the seroprevalence of Toxoplasma infection and associated risk factors in individuals attending a Reference Laboratory in Gorgan, Iran. Moreover, recent studies in Golestan province were reviewed. Materials and methods: A descriptiv...
objective: the aim of the present study was to investigate the effect of protein and dna components of toxoplasma gondii on maturation of dendritic cells and their efficiency in il-12 production and proliferation of t cells. materials and methods: for dc generation, bone marrow cells were cultured in the presence of gm-csf and il-4 for 5 days. tumor lysate and protein or dna components of toxo...
Background and purpose: Toxoplasmosis is a common zoonotic disease that is of particular importance in women before and during pregnancy. Therefore, this study aimed at investigating the seroepidemiology of Toxoplasma gondii in pregnant women and its risk factors in Golestan province, north of Iran. Materials and methods: A descriptive cross-sectional study was carried out in 440 blood samples...
background: toxoplasma gondii is the most common parasite causing latent cerebral infections in human. it has been shown that some anti-psychotic drugs are able to inhibit the proliferation of the parasite in in vitro study. there is very limited data regarding the inhibitory effect of anti-psychotics on toxoplasma in in vivo . in this study, we evaluated anti- toxoplasma activity of fluphenazi...
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