abstract background: inappropriate prescription of vancomycin has been shown to be asso- ciated with induction of antibiotic resistance. the objective of this study was to deter- mine the incidence of inappropriate use of vancomycin in a tertiary care hospital in iran. methods: a descriptive cross-sectional investigation was performed from september 2004 to march 2005 in all units of a general ...

background in recent decades, bacterial antibiotic resistance (especially in enterococci) has become a significant problem for human and veterinary medicine. one of the most important antibiotic resistances in enterococci, vancomycin resistance, is encoded by van gene family. objectives the aim of this study was to investigate antibiotic resistance to vancomycin in enterococci and the genes res...

b ackgro un d : staphylococcus aureus is a major human pathogen world wide. vancomycin has been used for decades to treat multidrug resistant s. aureus. ten years has passed since the first report of vancomycin re sistant s. aureus (vrsa). the objective of this systematic review was to determine  the total number of vrsa isolates that have been reported from iran. me t h ods :   search terms re...

conclusions: ten percent of the isolates were positive for meca gene among the vancomycin-oxacillin resistant strains, while van gene was not detected in any of the isolates. the data obtained would be useful in clinical control of resistant staphylococcal strains. results: a total of 120 staphylococcus isolates were screened, out of which, 32 (26%) were susceptible to both methicillin and vanc...

conclusions: the combination of plasmid profiling and php techniques revealed the presence of diverse population of vre in sewage treatment plant in tehran. furthermore, the results showed that the php technique is a reliable method in determining the vre clonal diversity. results: all isolates were found to be resistant to erythromycin, ampicillin and ciprofloxacin. the pcr analyses showed tha...

objective(s) staphylococcus aureus is a common cause of human infection, and emergence of vancomycin-resistance s. aureus  is a great concern for treatment of methicillin-resistant s. aureus,(mrsa) in recent years (mrsa). here, we report the isolation of high-level vrsa. materials and methods s. aureus was isolated from foot ulcer of a diabetic woman in tehran, iran. antibiotic susceptibility w...

background vancomycin resistant isolates of enterococcous faecium (vre) have previously been reported from tehran hospitals. however, little data were available on the genetic heterogeneity of vre isolates among the iranian population. therefore the emergence of infections with the new clones of vre needs to be investigated. the drug resistance surveillance program at labbafinejad hospital has ...

Staphylococcus aureus is colonized in the human nasal cavity and would contaminate hospital and therapeutic environments. This bacterium has a genetic diversity in terms of resistance to antimicrobial agents. Therefore, the purpose of this study was identificatied of Methicillin and Vancomycin resistant genes in Staphylococcus aureus strains which has been isolated from the nasal cavity. 189 pa...

conclusions vancomycin, but not teicoplanin, can be considered an effective antibiotic of choice for controlling infections caused by mdr cons in gorgan, depending on the bacterial species. background coagulase-negative staphylococci (cons) are clinically important, especially in nosocomial and neonatal infections. the increasing emergence of glycopeptide-resistant cons has made these agents th...