background: to explore the oral absorption of scorpion venom an elisa were designed in this study. scorpions and their venom were been used for centuries as medical treatments in traditional medicine. the oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of me...

buthotus schach is one of the dangers scorpion in iran that belong to the buthidae family. toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. in the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...

Conventional treatment of Naja naja oxiana (NNO) envenoming requires large volumes of equine antivenin raised against NNO crude venom. The poor efficiency of this antivenin is assumed to be due to the high molecular weight non-toxic proteins, a strong immunogen, present in the crude venom. These proteins cause depression of antibody formation against the low molecular weight toxic components of...

conventional treatment of naja naja oxiana (nno) envenoming requires large volumes of equine antivenin raised against nno crude venom. the poor efficiency of this antivenin is assumed to be due to the high molecular weight non-toxic proteins, a strong immunogen, present in the crude venom. these proteins cause depression of antibody formation against the low molecular weight toxic components of...

b a ckground: scorpions stings are a health problem in many parts of the world. mesobuthus eupeus (buthidae) is the most prevalent species in the middle east and central asia. definition of toxicogenic and immunogenic characteris- tics of the venom is necessary to produce antidote. in this study, the noted properties of m. eupeus venom were eval- uated. m e t hods: venom was obtained by milking...

neutralization effects of acorus calamus and withania somnifera root extracts were tested against echis carinatus venom. both plant extracts were effectively neutralized the various pharmacological activities induced by echis carinatus venom. about 0.14 mg of acorus calamus and 0.16 mg of withania somnifera root extracts were able to completely neutralize the lethal activity of 2ld 50 of echis ...

temporary paralysis is a rare manifestation of envenoming following the yellow iranian scorpion, odontobuthus doriae (o. doriae). thus, to elucidate the underlying mechanism, we investigated the neurotoxic effect of venom in the sciatic nerve, the possible mechanism in a mice model. the neurotoxicity and temperature effects in the venom-induced neurotoxicity were examined using the mouse sciati...