conclusions in summary, there is a lack of consensus about the use of neuromuscular blockers in patients with ibm. the authors avoided these drugs and were able to easily secure the patient’s airway and maintain adequate muscle relaxation using a balanced sevoflurane-remifentanil anesthetic. clinical trials are necessary to define the pharmacology of neuromuscular blockers in patients with ibm ...

muscle diseases constitute a large variety of both acquired and hereditary disorders that can affect muscle structure, metabolism, or the function of the muscle channel. a successful clinical approach to a patient with a suspected myopathy is based on a thorough medical history and neurological examination. associated clinical symptoms such as myoglobinuria, contractures, myotonia, cardiac dise...

neuromuscular disorders encompass a broad spectrum of disorders from the anterior horn cell to the muscle tissue itself. the given condition can be either genetic or acquired. these group of disorders are diagnostically challenging as many of them also pose other systemic findings. one example would the commonly seen mental retardation in duchenne muscular dystrophy. from the practical point of...

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Muscle weakness is common in the surgical intensive care unit (ICU). Low muscle mass at ICU admission is a significant predictor of adverse outcomes. The consequences of ICU-acquired muscle weakness depend on the underlying mechanism. Temporary drug-induced weakness when properly managed may not affect outcome. Severe perioperative acquired weakness that is associated with adverse outcomes (pro...

Rhabdomyolysis is characterized by severe acute muscle injury resulting in muscle pain, weakness, and/or swelling with release of myofiber contents into the bloodstream. Symptoms develop over hours to days after an inciting factor and may be associated with dark pigmentation of the urine. Serum creatine kinase and urine myoglobin levels are markedly elevated. Clinical examination, history, labo...

Congenital smooth muscle hamartoma usually manifests at birth, but rarely, can also appear later in life. It is usually located on the trunk and extremities and appears as variably‐sized papules, patches, or plaques.[3] Pseudo‐Darier’s sign is considered as the characteristic diagnostic clue for congenital smooth muscle hamartoma.[1] Pseudo‐Darier’s sign is a transient piloerection and elevatio...

Smooth muscle hamartoma is an uncommon, usually congenital, cutaneous hyperplasia of the arrectores pilorum muscles. When it is acquired, it may be confused with Becker's nevus. We report a case of this rare tumor in a 19-year-old man. The disease started several years ago as multiple small skin-colored papules that subsequently coalesced to form a large soft plaque on the back of the left shou...

A quantitative sonoelastographic technique for skeletal muscle tissue characterization is introduced. Experimental data was collected in both ex vivo bovine and in vivo human skeletal muscle tissue. Crawling wave sonoelastographic data was processed using a quantitative technique for estimating local shear wave speed distributions. Results on ex vivo skeletal muscle samples demonstrate shear wa...