background and objectives: endophytic actinobacteria colonize inside the plant tissues without causing damages to the host plant. since these microorganisms colonize in the different parts of plants and can stop plant disease, they have been applied as biological agents for controlling human diseases. the aim of this study was molecular identification and measuring the antimicrobial activity of...

atmospheric nitrogen fixation as an exclusive phenomenon is accomplished by nitrogenase enzyme of prokaryotic microorganisms namely diazotrophs including bacteria, actinomycets and cyanobacteria. nitrogen fixation is accomplished as form of symbiotic, associative and free-living systems. in free-living systems nitrogen is fixed without the help of plants. azotobacter, the first diazotroph was d...

Antibiotic drug discovery is an indispensable process to combat aggressive ability of pathogenic microorganisms and emerging infectious diseases against health and well-being of people throughout the world. According to the updated and expanded data on natural products presented by Newman and Cragg (2012), the utility of natural products as sources of novel structures is still alive and the ant...