kawasaki disease is a multi system disorder with varying clinical expressions. this disease is an acute systemic vasculitis of unknown etiology that has recently recognized as a leading cause of acquired heart disease in children of many developed countries. we describe an unusual instance of hair loss in a patient with kawasaki disease. a 26 months old boy developed prolonged high fever, bilat...

background: sub-acute bacterial endocarditis (sbe) rarely presents with features of a small vessel vasculitis. patients with sbe can also develop multiple serological abnormalities including anca. in this report, we present a case of infective endocarditis mimicked anca associated glomerulonephritis.case presentation: a 57-year old male with a clinical picture of rapidly progressive renal failu...

Volume 4 • Issue 1 • 1000124 J Data Mining Genomics Proteomics ISSN:2153-0602 JDMGP an open access journal Systemic vasculitis is a heterogeneous disorder characterized by chronic or acute inflammation, and is classified into groups by the size of the affected blood vessels: large vessel vasculitis, medium vessel vasculitis, or small vessel vasculitis. The pathogenesis of systemic vasculitis is...

BACKGROUND Monocytes have been suggested to play a role in antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis, but their state of activation in vivo in patients is still unknown. METHODS Twelve consecutive patients with acute anti-proteinase 3 (PR3)-positive vasculitis were included prospectively, and blood samples were drawn at diagnosis. As controls, peripheral blood was obtaine...

CONTEXT Levamisole-contaminated cocaine is an increasingly reported cause of vasculitis and immunologic abnormalities in cocaine abusers. The systemic effects of vasculitis are commonly seen in the dermatologic, hematologic and renal systems but rarely the gastrointestinal system. CASE REPORT We present an atypical case of cocaine-induced vasculitis presenting initially as an acute pancreatit...

BACKGROUND Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals. The reported treatment options for Acute Multifocal H...

Pulmonary-renal syndrome refers to patients with DAH (or pathologic pulmonary purpura on physical examination implies a small-vessel, cutaneous vasculitis ( 10).. The ANCA-associated vasculitides, WG, CSS, and MPA, are grouped. . The syndrome is characterized by a triad of (1) asthma, (2) hypereosinophilia, and . Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatos...

A 21-year-old male presented with acute onset, sharp right sided testicular pain. The testicle was removed with a histological diagnosis of testicular vasculitis. Anti-neutrophil cytoplasmic antibodies were negative. Although rare, males who present with acute onset pain should be screened for testicular vasculitis with a scrotal ultrasound and blood investigations including tumor markers and a...

BACKGROUND Acute dermatologic conditions are a concern for acute care practitioners. Comprising 1.4% of presenting complaints to emergency departments, most skin complaints are relatively benign; however, some conditions can be quite severe. Prompt diagnosis is essential to avoid unnecessary morbidity and mortality. OBJECTIVES To review drug-induced vasculitis. CASE REPORT We present the ca...

In the past, necrotizing vasculitis has been considered to be one of the dominant intrarenal vascular abnormalities in systemic lupus erythematosus (SLE). To test the validity of this statement, 70 consecutive renal biopsies from patients with SLE were reviewed. Light microscopy (LM) and immunofluorescence (IF) studies documented abnormalities, including thrombosis and nephrosclerosis, in 30 pa...