نتایج جستجو برای: adad
تعداد نتایج: 72 فیلتر نتایج به سال:
BACKGROUND The Adolescent Drug Abuse Diagnosis (ADAD) and Health of Nation Outcome Scales for Children and Adolescents (HoNOSCA) are both measures of outcome for adolescent mental health services. AIMS To compare the ADAD with HoNOSCA; to examine their clinical usefulness. METHODS Comparison of the ADAD and HoNOSCA outcome measures of 20 adolescents attending a psychiatric day care unit. ...
The concurrent and predictive validity of the Adolescent Drug Abuse Diagnosis (ADAD) in the Psychological status and problem area was examined for two adolescent groups: a non-clinical population of 121 Swedish adolescents (62 girls and 59 boys) aged 15 to17 years and a clinical population of 31 adolescents (14 girls and 17 boys) aged 12 to 19 years detained in special youth homes. Concurrent v...
Fast, inexpensive, and noninvasive identification of Alzheimer's disease (AD) before clinical symptoms emerge would augment our ability to intervene early in the disease. Individuals with fully penetrant genetic mutations causing autosomal dominant Alzheimer's disease (ADAD) are essentially certain to develop the disease, providing a unique opportunity to examine biomarkers during the preclinic...
OBJECTIVE The aim of this study was to evaluate a French language version of the Adolescent Drug Abuse Diagnosis (ADAD) instrument in a Swiss sample of adolescent illicit drug and/or alcohol users. PARTICIPANTS AND SETTING The participants in the study were 102 French-speaking adolescents aged 13-19 years who fitted the criteria of illicit drug or alcohol use (at least one substance--except t...
OBJECTIVE The purpose was to describe clinical, cognitive, and personality characteristics at baseline assessment of 249 participants, 19 to 60 years of age, in a multinational longitudinal study of autosomal dominant Alzheimer's disease (ADAD). METHOD Participants (74% cognitively normal) were from ADAD families with mutations in 1 of 3 genes (APP, PSEN1, or PSEN2). Mixed model analyses, inc...
Psychometric Studies of the Swedish Version of the Adolescent Drug Abuse Diagnosis (ADAD) Instrument
Börjesson, J. (2011). Psychometric studies of the Swedish version of the Adolescent Drug Abuse Diagnosis (ADAD) Instrument. Doctorial Dissertation from the Department of Psychology, Umeå University, S-901 87 Umeå, Sweden: ISBN: 978-91-7459-317-4. This thesis describes studies into the psychometric properties of a Swedish language version of the Adolescent Drug Abuse Diagnosis (ADAD) instrument....
Studying autosomal dominant Alzheimer's disease (ADAD), caused by gene mutations yielding nearly complete penetrance and a distinct age of symptom onset, allows investigation of presymptomatic pathological processes that can identify a therapeutic window for disease-modifying therapies. Astrocyte activation may occur in presymptomatic Alzheimer's disease (AD) because reactive astrocytes surroun...
IMPORTANCE Brain imaging and fluid biomarkers are characterized in children at risk for autosomal dominant Alzheimer disease (ADAD). OBJECTIVE To characterize and compare structural magnetic resonance imaging (MRI), resting-state and task-dependent functional MRI, and plasma amyloid-β (Aβ) measurements in presenilin 1 (PSEN1) E280A mutation-carrying and noncarrying children with ADAD. DESIG...
The Dominantly Inherited Alzheimer Network (DIAN) is a collaborative effort of international Alzheimer disease (AD) centers that are conducting a multifaceted prospective biomarker study in individuals at-risk for autosomal dominant AD (ADAD). DIAN collects comprehensive information and tissue in accordance with standard protocols from asymptomatic and symptomatic ADAD mutation carriers and the...
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