نتایج جستجو برای: adipose tissue derived mesenchymal stem cells

تعداد نتایج: 2471378  

ارجمند, ساره, سلیمانی, مسعود, صاحبقدم لطفی, عباس, قانعی الوار, حوری, مشهدی عباس, فاطمه,

Background and purpose: Chronic non-healing diabetic wounds are a major medical challenge worldwide. Stem cell therapy has been developed as a new approach in the management of such wounds that need to be explored further. In the present study we aimed to evaluate the effects of adipose derived mesenchymal stem cells (ADSCs) on gene expression level of some important inflammatory factors involv...

Ali Mohammadsharifi, Farzaneh Tafvizi, Gholamabbas Nasr, Mahdieh Ghiasi, Mohammad Bigdelo, Mohammad Mehdizadeh, Neda Tekiyeh Maroof, Sahar Farzaneh, Sedigheh Safari,

Background and Aims: Cartilage is a very specific tissue, which does not have the capacity to heal and renew itself. Although the invention of the method of surgery with autologous chondrocyte transplantation, developed tools to treat the cartilage lesions, it couldn’t gain a great success due to problems such as damage to the area of donation. Using the mesenchymal stem cells derived from adip...

Journal: :modares journal of medical sciences: pathobiology 2014
nahid davoodian abbas sahebghadam lotfi masoud soleimani seyed javad mola

objective: micrornas (mirnas) are noncoding rnas that function as key regulators of diverse biological activities such as cellular metabolism, cell proliferation and cell cycle regulation. recent studies have indicated the high potential of these small molecules to control stem cell differentiation into desired cells. the aim of present study is to investigate the possible effect of let-7f on e...

Aida Java Zadeh, Ali Shariat Razavi, Mohammad Reza Khojasteh, Sajad Sahab Negah,

Neuroinflammation has a significant role in induce of Multiple sclerosis (MS) many approaches have been used to treat MS, but none of these methods have not been able to fully improve. One of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. Using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuroinfla...

Journal: :international journal of preventive medicine 0
batool hashemibeni farzaneh jafary nafiseh esmaeil vahid goharian ghader feizi fariba heidary

background: characteristics of differentiated osteoblasts from adipose derived stem cells (adscs) in compared with isolated osteoblasts from normal bone such as calvaria are unknown. the aim of this study was determination and comparison of phenotypic characterization between differentiated osteoblasts from stem cells and calvaria osteoblasts in vitro . methods: in this study, mesenchymal stem ...

Journal: :world journal of plastic surgery 0
davood mehrabani stem cell and transgenic technology research center, department of pathology, shiraz university of medical sciences, shiraz, iran golshid mehraban student research committee, school of dentistry, international kish branch, shiraz university of medical sciences, shiraz, ira shahrokh zare stem cell and transgenic technology research center, department of pathology, shiraz university of medical sciences, shiraz, iran ali manafi department of plastic surgery, tehran university of medical sciences, tehran, iran

in cell therapy and regenerative medicine, a reliable source of stem cells together with cytokine growth factors and biomaterial scaffolds seem necessary. as adipose tissue is easy accessible and is abundant source of adult stem cells and can differentiate along multiple lineages, it can be considered as a good candidate in aesthetic medicine. the clinical application of adipose-derived stem ce...

Journal: :Journal 2008
George K B Sándor Riitta Suuronen

Interdependency exists between adipogenesis, the formation of fat tissue from stem cells, and osteogenesis, the formation of bone from its stem-cell precursors. Adipose-derived adult mesenchymal stem cells may be useful for future bone regeneration and tissue engineering. This review discusses potential future relationships between autogenous adipose-derived stem cells, growth factors and resor...

Fani Maleki A Nazari F, Parham A

Background: Adipose tissue is a main source for isolation of equine mesenchymal stem cells (MSCs) at different ages. It seems that characteristics of adipose-derived MSCs especially gene expression profile are changing along with age increase. A proper reference gene is required for normalizing data in gene expression analysis by qRT-PCR. This study aimed to evaluate whether GAPDH has a stable ...

Mohammadreza Alijani, Moosa Javdani, Rasool Rahimi Junqani,

Spinal cord injury (SCI) is a neurologic disorder that have a significant impact on quality of life, life expectancy, and economic burden. SCI leads to irreversible neuronal loss and ultimately leads to paralysis. Mesenchymal stem cells (MSCs) are a promising source for cellular therapy because they have possessed the capacity of self-renewal and differentiation to several distinct mesenchymal ...

Journal: :iranian journal of blood and cancer 0
a salimi m ghollasi n saki f rahim a dehghanifard sh alizadeh

stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. today, nanofibrous scaffolds are widely used in tissue engin...

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