OBJECTIVES We sought to compare dobutamine-atropine stress echocardiography (DASE) and dipyridamole Technetium 99-m (Tc-99m) sestamibi single photon emission computed tomography (SPECT) scintigraphy (DMIBI) for detecting coronary artery disease (CAD). BACKGROUND Both DASE and DMIBI are effective for evaluating patients for CAD, but their concordance and limitations have not been directly comp...

L. Stehly,1,2 B. Fry,3 M. Campillo,1 N. M. Shapiro,4 J. Guilbert,2 L. Boschi3 and D. Giardini3 1Université Joseph Fourier, CNRS, LGIT, BP 53, 38041 Grenoble, France. E-mail: [email protected] 2CEA/DASE, BP 12, 91680 Bruyères-le-Châtel, France 3Institute of Geophysics, ETH Zurich, Hönggerberg HPP, CH-8093 Zurich, Switzerland 4Laboratoire de Sismologie, CNRS, IPGP, 4 place Jussieu, 75252 Paris...

A software architecture evaluation is a way to assess the quality of the technical design of a product. It is also a prime opportunity to discuss the business goals of the product and how the design bears on them. But architecture evaluation methods are seen as hard to learn and costly to use. We present DASE, a compact approach that combines carefully selected key parts of two existing archite...

OBJECTIVE The purpose of the present study was to provide evidence regarding the safety of real-time flash-contrast echocardiography combined with dobutamine-atropine stress echo (DASE). BACKGROUND The combination of perfusion assessment using myocardial contrast echocardiography (MCE) with DASE has shown very promising results for the diagnosis of coronary artery disease. Concerns have, howe...

BACKGROUND We aimed to compare the incremental value of contrast myocardial perfusion imaging (MPI) for the detection of intermediate versus severe coronary artery stenosis during dipyridamole-atropine echocardiography (DASE).Wall motion (WM) assessment during stress-echocardiography demonstrates suboptimal sensitivity to detect coronary artery disease (CAD), particularly in patients with isola...

A suspension of Chang's hepatoma cells was inoculated into the tail vein of rats. Rats were killed at different intervals ranging from 30 seconds to 3 hours. Peroxi dase-labelled goat anti-rabbit gamma globulin was applied to the tissue by an in direct method. Peroxidase-positive material was always found between the tumor cell and the endothelial lining and at the center of the 'platelet tail'...