In present study possible ameliorative efficacy of aqueous extract of bark of Alstonia scholaris (ASE) in cultured human lymphocytes against Bleomycin-induced cytogenetic alterations has been reported. Cultures were treated either alone with Alstonia scholaris aqueous bark extract (50μg/ml) or in combination with radiomimetic drug Bleomycin (15μg/ml). Positive implications about radioprotective...

A new steroid, 3-hydroxy adiantulanosterol (5), together with four known compounds, were isolated from the stem bark of Alstonia scholaris. All structures were elucidated by spectroscopic methods.

There is an urgent need for a biodegradable, hydrophobic material that can be used in developing packaging materials. In this preliminary study, epicuticular wax has been extracted from the leaves of Calotropis procera and Alstonia scholaris using various solvents (i.e., ethanol, methanol, benzene, and acetone). The highest wax amounts were found to be 0.54 μg/cm2 and 0.13 μg/cm2 from Alstonia ...

Aim: Snake envenomation is a major cause of death and disability in the developing countries, particularly in South East Asia. Since 1894, commercial snake venom antiserum developed by Calmette is the only specific treatment available for snake bite. The use of plants against the effects of snakes bite has been long recognized; more scientific attention has been given since last 20 years (Santo...

The present work is carried out to evaluate the antioxidant potential of fractions from ethanolic extract of Alstonia scholaris Linn. (Apocynaceae) using various in vitro tests including 1,1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging, metal ion chelating, hydrogen peroxide scavenging, superoxide anion radical scavenging, and ferric thiocyanate reducing ability. Dichloromethane an...

Alstonia scholaris has been used by traditional medicine practitioners since the medieval ages for the treatment of diseases. The aim of this research was to evaluate the acute and sub-acute oral toxicity of its methanolic extract. The acute toxicity test was conducted using Sprague Dawley (SD) rats. The methanolic extract of Alstonia scholaris stem bark (ASME) was administrated in a single dos...

Alstonia scholaris is a traditionally important medicinal plant. This evergreen tree is native to the Indian subcontinent and Southeast Asian countries. The plant is used in traditional, Ayurvedic, Unani, Homoeopathy and Sidhha/Tamil types of alternative medicinal systems against different ailments such as asthma, malaria, fever, dysentery, diarrhea, epilepsy, skin diseases, snakebite etc. Amon...

the present work is carried out to study the antioxidant potential of ethanolic extract of alstonia scholaris linn. ( apocynaceae ) using various in vitro tests including 1,1-diphenyl-2-picryl-hydrazil (dpph . ) free radical scavenging, metal ion chelating, hydrogen peroxide scavenging, superoxide anion radical scavenging, and ferric thiocyanate reducing ability.   ethanolic extract of alstonia...

The present work is carried out to study the antioxidant potential of ethanolic extract of Alstonia scholaris Linn. ( Apocynaceae ) using various in vitro tests including 1,1-diphenyl-2-picryl-hydrazil (DPPH . ) free radical scavenging, metal ion chelating, hydrogen peroxide scavenging, superoxide anion radical scavenging, and ferric thiocyanate reducing ability.   Ethanolic ex...

Topical retinoids inhibit matrix metalloproteinases and accelerate collagen synthesis, thereby triggering antiaging effects in the skin. However, topical retinoids can cause severe skin reactions, including scaling, erythema, papules, and inflammation. The present study demonstrates that the ethanolic bark extract of Alstonia scholaris R. Br. can significantly inhibit all-trans retinoic acid-in...