purpose: to evaluate the use of amniotic membrane transplantation (amt) for management of congenital distichiasis. methods: this interventional case series was performed on 16 eyelids of 5 patients with congenital distichiasis treated with posterior lamella resection and amt. results: all patients were men aged 2 to 42 years. mean follow up was 17 months (6-29 months). post-operative symptoms o...

purpose: to evaluate the effect of amniotic membrane transplantation in trabeculectomy. methods: the study was conducted on 25 eyes of 25 patients with advanced and medically uncontrolled glaucoma. all patients underwent trabeculectomy with a fornix based conjunctival flap, amniotic membrane was then placed under the scleral flap and fixed using 10-0 nylon suture. amniotic membrane was retrieve...

Background & Aims: Amniotic membrane persists for a long time after ocular transplantation (as corneal substitute) and can affect light transmission (transparency). The aim of this study was to evaluate the transparency of amniotic membrane after freeze-drying (lyophilization) and to compare the results with transparency of rabbit cornea. Methods: Transparency of rabbits’ corneas and fresh and ...

purpose: to evaluate the effect of aamniotic mmembrane ttransplantation (amt) in the management of acute severe ocular chemical burns. methods: this randomized clinical trial was performed in eligible patients with grade iii & iv acute chemical burn who randomly received conventional medical therapy (15 eyes) versus combined medical & amniotic membrane transplantation (15 eyes). main outcome me...

the past decade has witnessed the revival of amniotic membrane transplantation (amt) in ophthalmology. the importance of amt is due to its ability to reduce scarring and inflammation and to enhance wound healing and epithelialization, and also its anti-microbial properties. amniotic membrane has recently been used as a substrate for culturing limbal stem cells for transplantation. it has been u...

purpose: to compare outcomes and recurrence rates of amniotic membrane transplantation (amt) plus intraoperative mitomycin c (mmc) and conjunctival rotational autograft (cra) plus intraoperative mmc in pterygium surgery methods: ninety-two eyes of 92 patients with primary nasal pterygium were enrolled. all patients were randomized to undergo either amt or cra. forty-three patients underwent amt...

PURPOSE Amniotic membrane transplantation is currently being used as an alternative approach to treat severe corneal surface disorders refractory to medical therapy. The authors report complications of corneal surface disorders after successful amniotic membrane transplantation. METHODS Case series. RESULTS Twenty-eight patients with corneal surface disorders due to severe chemical burns, c...

PURPOSE The immunogenic characterization of amniotic membrane is still unknown. This study was designed to examine the immunogenicity of human amniotic membrane, by using experimental xenotransplantation models. METHODS Anti-human class I, class II, and Fas ligand monoclonal antibodies were used against cryopreserved amniotic membrane and cell viability tested for cryopreserved amniotic membr...