introduction: scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (amps) have been found in the venom gland of scorpions. therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. here, we describe three new cationic amps, including meuvap-6, meuap-18-1, and meupep34 from the ve...

Antimicrobial peptides (AMPs) are natural products found across diverse taxa as part of the innate immune system against pathogen attacks. Some AMPs are synthesized through the canonical gene expression machinery and are called ribosomal AMPs. Other AMPs are assembled by modular enzymes generating nonribosomal AMPs and harbor unusual structural diversity. Plants synthesize an array of AMPs, yet...

Antimicrobial Peptides (AMPs) were first known as a group of innate immune products that mainly targets on the invading pathogens among multiple species. The essential mechanisms of action of AMPs toward microbial cells have been reported as electrostatic attraction and hydrophobic interaction between AMPs (cationic AMPs) and microbial cell membranes. These effects also contribute to the potent...

Cellular digital packet data (CDPD) networks borrow idle radio channels from advanced mobile phone standard (AMPS) cellular networks to send packet data traffic. We explore the amount of unused AMPS capacity available to parasitic data networks such as CDPD. Due to trunking inefficiencies, a relatively large amount of spare AMPS airlink capacity can be found. In addition, the periods of time AM...

Distributed load balancers exhibit thrashing where tasks are repeatedly moved between locations due to incomplete global load information. This paper shows that systems of Autonomous Mobile Programs (AMPs) exhibit the same behaviour, and identifies two types of redundant movement (greedy effect). AMPs are unusual in that, in place of some external load management system, each AMP periodically r...

Autonomous Mobile Programs (AMPs) are mobile agents that are aware of their resource needs and sensitive to the execution environment. AMPs are unusual in that, instead of using some external load management system, each AMP periodically recalculates network and program parameters and independently moves to a new location if it provides a better execution environment. Dynamic load management em...

The frequent emergence of drug-resistant bacteria has created an urgent demand for new antimicrobial agents. Traditional methods of novel antibiotic development are almost obsolete. Antimicrobial peptides (AMPs) are now regarded as a potential solution to revive the traditional methods of antibiotic development, although, until now, many AMPs have failed in clinical trials. A comprehensive data...